Manar Ali Mohamed, Sherif Farouk Elgayar, Enas Alaa Eldin Abd Elaziz, Marwa Tammam Amin And Shima Gafar Mansor,

ABSTRACT
Background: Malignant Salivary Gland Tumors (MSGTs) Are A Heterogeneous Group Of Tumors With Significantvariability In Their Microscopic Appearance And Biological Behavior. Their Clinical Presentation Can Vary According To The Lesions. AgNOR Staining Is Valuable As A Marker Of Cellular Proliferation. The Present Study Aims To Evaluate The Role Of AgNORs Staining And Its Correlation With Tumor Type And Lymphovascular Invasion (LVI) In MSGTs. Methods:The Current Study Was Performed On 40 Malignant Salivary Gland Tumors (22 Cases Of Mucoepidermoid Carcinoma (MEC), 14 Cases Of Adenoid Cystic Carcinoma (ACC), 2 Cases Of Myoepithelial Carcinoma (MECA) And 2 Cases Of Acinic Cell Carcinoma (AciCC).

Results: The AgNORs Count Was Statistically Significantwith Tumor Type And LVI. A Higher Median AgNOR Was Noted In ACC (2.29) While A Lower Median AgNOR Was Associated With MECA (1.51). Conclusion: Analysis Of AgNORs Is Valuable As A Reliable Predictive Marker Of Clinical Behavior Of Malignant Salivary Gland Tumors (MSGTs).