Reham Hassan Fathy Abo-Rekiba, Olfat El-Sayed Hassanein And Rasha Raafat Hassan,

ABSTRACT

Objectives: The Aim Of This Study Was To Compare In Vivo The Efficacyof Polishing Paste Containing Either Nano-hydroxy Apatite Or 5% Calcium Sodium Phosphosilicste (NovaMin), And A Non-desensitizing Polishing Paste (Placebo Paste), On Dentin Hypersensitivity In A Four-week, Double-blind Clinical Study.Methods: This Was A Randomized, Single-center, Controlled, Three Treatment, Parallel-group Study Conducted At Faculty Of Dentistry Operative And Restorative Department Cairo University.155 Male And Female Subjects Who Met All Inclusion/exclusion Criteria And Had At Least Two Sensitive Teeth Based On Tactile , Air Blast And Cold Assessments, Were Enrolled In The Study. At Baseline, Tactile Air Blast And Cold Stimuli Were Administered And Subjects Were Stratifiedaccording To Their Diagnosis Scores Into One Of Three Treatment Groups: Group D1 (placebo Paste), Group D2 (NovaMin Without Fluoride)or Group D3 (Nano-hydroxy Apatite). Subjects Were Then Assessed Post-treatment At Bassline (T1), 2 Weeks (T2) And 4 Weeks (T3), Vissual Analogue Scale (VAS) Was Taken Before And After Materials Application At The Three Time Intervals Participants Were Instructed Not To Use Other Oral Hygiene Products Or Any Other Dental Treatment For Hypersensitive Teeth, And Drugs Like Analgesics That May Alter The Pain Perception Within 24 Hrs Of The Assessment Days. Participants Were Instructed Not To Use Any Tooth Paste That May Alter The Results Only Brushing Teeth W Ith Tooth Brush And Water Without Tooth Paste As It Depends On Brushing Motion .

Results: A Statistically Significantdifference Was Found Between (D1) And Each Of (D2) And (D3) Groups In All Three Tests Where (p<0.001).The Lowest Mean Value Of Pain Score Was Found In Nano-hydroxy Apatite (D3) Followed By Novamin (D2) , While The Highest Mean Value Of Pain Score Was Found In Placebo (D1). Also, A Statistically Significantdifference Was Found Between (Base-line) And Each Of (After 2 Weeks) And (After 4 Weeks) Groups Where (p<0.001) And A Statistically Significantdifference Was Found Between (After 2 Weeks) And (After 4 Weeks) Where (p<0.001) In All Tactile, Air And Cold Tests. Conclusion: Under The Limitation Of This Study Reduction Of Dentine Hypersensitivity Was Obviously Apparent For Either Nano-hydroxy Apatite And Novamin Throughout The Time Interval Of This Study. Superior Effect Of Novamin Was Observed Immediately After Its Application . While The Effect Of Nano-hydroxy-appatite Regarding Reduction Of Dentine Hypersensitivity Was Time Dependent.