Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Abdel Hafe And Salah Abdel Fattah Ahmed,

ABSTRACT


Purpose: The Aim Of The Study Is To Compare Histologically Between Autogenous Bone Graft And The Composite Of Bone Marrow Concentrate And Alloplast In The Repair Of Calvarial Bony Defects In White New Zealand Rabbits. Methodology: The Study Was Conducted On 14 Standardized Surgically Created Defects In Seven White New Zealand Rabbits With Weights Ranging From Three To Four Kilograms. Each Rabbit Was Submitted To Two Standardized Surgical Defects At The Parietal Bone. The Defects Were Randomly Allocated Into Two Groups According To Defect Filling As Follows: Group A (n=7), The Defects Were Grafted Using A Composite Of Bone Marrow Concentrate (BMC) And An Alloplastic Scaffold; Group B (n=7), The Defects Were Grafted Using Autologous Bone Graft. Animals Were Sacrificed Eight Weeks Post-operative And Histo-morphometric Assessment Was Done To Calculate The Percentage Of Newly Formed Bone With Regard To The Defect Size.

Results: There Was No Statistically Significant Difference (p>0.05) Between The Two Groups Regarding The Percentage Of Newly Formed Bone. Conclusion: The Use Of Bone Marrow Concentrate Enhanced Alloplast To Reconstruct Surgical Defects Is A Reliable Alternative To Autogenous Bone Graft.