REGENERATIVE MEDICINE FOR WOUND HEALING IN IRRADIATED MODELS. REVIEW ARTICLE

Arwa M. Diaa Eldin Hamed; Azza Ezz El-Arab; Eman Mohamed Fathy El Maghraby And Dina Sabry,

ABSTRACT
Normal Wound Healing Process Undergoes Multiple Stages Of Healing. Normal Wound Healing Mechanism Is Interrupted By Radiation Therapy; Patients Who Receive Radiotherapy Suffer From Delayed Wound Healing. Treatment Of Irradiated Wounds Includes The Application Of Growth Factors, Special Dressings And Injection Of Cells. Many Studies Showed That Wound Healing Acceleration Could Be Obtained By Application Of Mesenchymal Stem Cells. Wounds Treated With Mesenchymal Stem Cells Seeded Into Hydrogels Such As Hyaluronic Acid Showed Acceleration In Wound Healing. The Hydrogel Is Used Widely In The Medical Field To Treat Inflammatory Process Due To Its Unique Physiochemical And Biological Properties.

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