Fatma Y. Abd ?El Hamid, Maged M. Negm, Eman Mohamed Fathy El Maghrabi And Ali Fahmy Mohamed,

ABSTRACT
The Purpose Of This Study Was To Evaluate The Effect Of Gamma Radiation On Biocompatibility And Surface Texture Of MTA, Ketac-Fil And Ketac-Silver. Methods: Effect Of Gamma Irradiation On Mineral Trioxide Aggregate (MTA), And Glass Ionomer Cements (Ketac-Fil And Ketac-Silver) Were Evaluated In Comparison To Non-irradiated Group Of The Same Materials. Ten Samples Of Each Subgroup Were Placed In Culture Medium For 7 Days. Non Treated Cells Were Used As A Negative Control. The Cell Cultures Were Incubated For 1,3 And 7days. Cytotoxicity Was Evaluated By Methyl Tetrazolium Assay (MTT) , And The Surface Changes Of The Set Materials Was Assessed By Using Scanning Electron Microscope (SEM). The Data Of Cell Cytotoxicity Were Analyzed Statistically By Using A One-way ANOVA Analysis Of Variance Test At A Significance Level Of P < .05.

Results: After 7 Days? Materials Exposed To Gamma Irradiation Were More Cytotoxic Than Non-irradiated Materials. However, After 1 Day Irradiated Ketac-Fil Followed By Ketac-Silver Were Less Cytotoxic Than Non-irradiated Keta-Fil And Ketac-Silver. MTA Showed The Highest Viabilities Followed By Ketac-Silver Then Ketac-Fil.