Eman A. S. Khalaf, Laila E. Amin, Ayman M. Nagib And Fatma M.M. Ibrahim,
ABSTRACT
Objective: Chronic Renal Failure Can Elicit A Wide Spectrum Of Oral Manifestations In The Hard And Soft Tissues. Many Studies Have Demonstrated The Efficacy Of Casein Phosphopeptide Amorphous Calcium Phosphate With Fluoride Paste In Promoting Remineralization Of Enamel And Dentin In Vitro. Design: This Study Was Designed To Determine The Effect Of Renal Insufficiency On Patients? Teeth (enamel And Dentin) And Study Biological Effects Of Topical Application Of Fluoride On Extracted Teeth.
Materials and Methods: Twenty Sound Posterior Teeth Were Used, Divided Into 2 Groups, Group I (control Group) And Group II (fluoride Group). Each Group Was Subdivided Into 2 Subgroups;
A (control) And B (uremic). All The Specimens Were Scanned By Using Scanning Electron Microscope And Elemental Analysis Of Enamel And Dentin Surfaces Was Tested Using Energy Dispersive Analytical X-ray.
Results: Enamel Of Uremic Teeth Showed Irregular Enamel Surface With Deep Depressions And Pitting. Also, Dentinal Tubules Showed Different Shaped Outlines And Diameter. The Application Of Fluoride Paste Was Significantly Increase In Calcium And Phosphorus Levels.
Conclusions: Chronic Renal Failure Leads To Alteration In The Structure Of Enamel And Dentin With Significant Increase In Mineral Content (Calcium & Phousphrous) When Compared With Healthy Teeth. The Topical Application Of Fluoride Was Effectively Enhanced The Remineralization And Counter Act Demineralization And Erosion.
