Lotfy Elsayed Lotfy, Abeer Abd El-Aziz El-Gindy And Mohammad Osama M.Shawky,

ABSTRACT


Aim: The Current Study Aimed To Evaluate The Antibacterial Effect Of Curcumin, Photoactivated Curcumin In Comparison To Sodium Hypochlorite As Root Canal Irrigating Solutions Against Enterococcus Faecalis. Methods: Sixty Extracted Single-rooted Mandibular Premolars With A Closed Apex Were Cleaned, Disinfected And Prepared. E. Faecalis�were Inoculated In The Disinfected Root Canals Which Were Randomly Divided Into Four Equal Groups Each Of 15 According To The Type Of Irrigant Used [group (1): Saline, Group (2): 2.6% NaOCl, Group (3): Curcumin And Group (4): Photoactivated Curcumin]. Samples From Each Group Were Subjected To Microbiological Assessment At Two-time Points; Before And After Root Canal Treatment With Different Irrigating Solutions; To Detect Viable Bacterial Cells Using MTT Assay. Collected Data Were Then Statistically Compared To Determine Differences Between The Tested Root Canal Irrigants.

Results: After Using Tested Irrigant Solutions, Photoactivated Curcumin And Sodium Hypochlorite Showed A Significant Antibacterial Effect Better Than Curcumin And Saline.

Conclusions: Within The Limitations Of The Present Study, The Antibacterial Effect Against Enterococcus Faecalis Of Photoactivated Curcumin Is Comparable To 2.6% NaOCl Regarding Its Use As Root Canal Irrigating Solution.