Ahmed Mohamed Ali, Siza Yacoub Zakhary And Suzan Abdul Wanis Amin,

Objectives: To Systematically Review And Provide A Pooled Effect Estimate For The Clinical Effects Of Calcium Hydroxide Intracanal Medication In Non-vital Mature Teeth. Data Sources: Electronic? Databases Searching, For Published And Grey Literature, And Manual Searching Were Conducted. Study EUgibility Criteria: Only Randomized Clinical Trials Were Included That Compared Calcium Hydroxide To Other Intracanal Medications In Non-vital Immature Teeth.Study Appraisal & Synthesis Methods: The Risk Of Bias Was Assessed Using The RoB 2.0 Cochrane Tool. The Main Outcomes Were Clinical Healing And Analgesic Intake. Risk Ratio Was Calculated For Dichotomous Data With Their 95% Confidence Intervals.

Results: Five Articles Reported In 4 Studies (N=285) Were Included In This Systematic Review. Calcium Hydroxide Was Compared To 6 Other Intracanal Medications. Calcium Hydroxide Had Similar Clinical Healing Effectiveness As Calcium Hydroxide Mixed With Iodoform And Povidine Iodine Paper Points (p-value >0.05) And Similar Effects On Analgesic Intake As Calcium Hydroxide Mixed With Chlorhexidine (P-value >0.05).Conclusion: Calcium Hydroxide Intracanal Medication Alone May Have Similar Clinical Effectiveness Compared To Calcium Hydroxide Mixed With Iodoform And Similar Effects On Analgesic Intake As Calcium Hydroxide Mixed With Chlorhexidine.