EFFICACY OF PREOPERATIVE ACECLOFENAC ON POST-ENDODONTIC PAIN: A RANDOMIZED CLINICAL TRIAL

Nermeen Awadallah Abbas Ibrahim, Suzan Abdul Wanees Aminand Shaimaa Ismail Gawdat,

ABSTRACT


Aim: The Aim Of This Prospective, Randomized, Double-blind, Clinical Trial Was To Evaluate The Effect Of A Preoperative, Single, Oral Dose Of Aceclofenac (100 Mg) On Postoperative Pain At 6, 24 And 48 Hours After Single-visit Root Canal Treatment. Methods: Seventy, Endodontic Emergency Patients With Symptomatic Irreversible Pulpitis (SIP) In Posterior Teeth, Randomly Received Either 100 Mg Aceclofenac (Group A, N=35) Or Placebo (Group B, N=35) Tablets 60 Minutes Before The Initiation Of Single-visit Endodontic Therapy. Postoperative Pain Intensity And Incidence At The Different Pain Categories (No, Mild, Moderate, Severe) Was Assessed 6, 24, And 48 Hours Postoperatively Using Heft-Parker Visual Analogue Scale (HP-VAS). Data Were Statistically Analyzed And The Significance Level (?) Was Set At 0.05.

Results: There Was No Significant Difference Between The Two Groups Regarding The Main Baseline Characteristics Including: Age, Gender, Pre-operative Pain And Canal-number Distribution (p>0.05). Results Showed No Significant Difference Between Both Groups Regarding Postoperative Pain Intensity Or Incidence 6, 24 And 48 Hours Postoperatively (p >0.05). Pain Intensity Significantly Decreased Over Time (p<0.05) Conclusion: Preoperative Administration Of A Single, Oral Dose Of 100 Mg Aceclofenac Did Not Seem To Affect The Postoperative Pain Within The First 48 Hours After Single-visit Root Canal Treatment.

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