Amr Helmy El Bolok, Enas Alaa El Din Abd El Aziz, Mai Ibrahim Sholqamy And Sara Moustafa Mahmoud,
ABSTRACT
Aim Of Study: To Investigate The Expression Of Ki-67 And Midkine In Salivary Gland Tumors And Evaluate The Correlation Between MK And Ki-67 Expression In SGTs.
Materials and Methods: Twenty Five Formalin Fixed Paraffin Blocks Of SGTs Were Stained Immunohistochemically For Ki-67 And MK. Immunostainig Was Measured As Area Fraction And Results Were Analyzed Statistically. Value <0.05 Was Considered Significant.
Results: All Cases Of SGT Showed Positive Reaction To Ki-67 And MK. A Significant Positive Correlation Was Found Between Ki-67 And MK Expression In SGTs.
Conclusion: MK And Ki-67 Expression Are Higher In Malignant Than Benign Salivary Gland Tumors, So Evaluation Can Provide Information About Aggressiveness Of The Tumor.
