Dina Kamal , Dalia A. El-Baz, Laila A. Rashed And Samah S. Mehanni,
ABSTRACT
Objectives: Traumatic Oral Lesions May Be Due To Physical, Thermal Or Chemical Injuries. Wound Healing By Secondary Intention Is Divided Into Three Phases: Inflammation, Proliferation, And Remodeling. Stem Cell Based Therapies Are Being Investigated For The Treatment Of Many Conditions. Miura Et Al. 2003 Isolated Stem Cells From Pulp Tissue Remnants Of Exfoliated Deciduous Teeth And They Termed Them Stem Cells From Human Exfoliated Deciduous Teeth (SHED). SHED Was Found To Have A Higher Proliferating Rate Than DPSCs And BM-MSCs Which Suggest That They Are A Less Mature Population Of Multipotent Stem Cells.
Design: Thirty Male Albino Rats Were Utilized, Fifteen As Control Group And Fifteen As SHED Group. The Tongues Were Dissected And Examined Histologically.
Results: The Histopathological Results Showed Complete Coverage Of The Surface Of The SHED Group At 7 Days While The Control Group Was Still Showing An Open Ulcer.
Conclusion: SHED Showed Better Healing Of Induced Wounds Compared With Control Group.
