Rehab Abdelrahman Elshenawy , Soad Abdelmoniem Abdelmoniem And Fatma Ahmed Hamdy Elshehaby,

ABSTRACT
Objective: This Study Was Conducted To Assess Effectiveness Of Ibuprofen And Paracetamol Versus Placebo On Pain Perceptions During Local Anesthetic Injection And Following Dental Extraction Of Lower Primary Molars In Children. Subjects And Methods: A Randomized Controlled Clinical Trial Was Performed On 156 Apparently Healthy Egyptian Children Who Were Enrolled From The Outpatient Clinic In Pediatric Dentistry And Dental Public Health Department- Faculty Of Dentistry, Cairo University- Egypt. The Participants Were Divided Into Three Groups (52 Patients In Each Group). Each Group Received Specific Type Of Drug 30 Minutes Before Local Anesthetic Administration. The First Group Received Ibuprofen, The Second One Received Paracetamol And The Third Group Received Placebo. Pain Scores During The Injection Of Local Anesthesia And Following Dental Extraction Were Recorded Using The Facial Image Scale (Five-Face Scale). Pain Scores Were Recorded At The 1st, 2nd, 3rd, 4th, 5th, 6th And 24th Hours Following Dental Extraction From Parents By Telephone.

Results: The Use Of Pre-emptive Analgesia As Ibuprofen And Paracetamol Decreased The Pain Scores Significantly Compared To Placebo During Local Anesthetic Administration. Additionally, At The Third, Fourth , Fifth, Sixth And 24th Hours Following The Dental Extractions, The Results Showed Statistically Significant Differences Between The Three Groups With (p?0.001). Conclusion: The Use Of Pre-emptive Analgesia As Ibuprofen And Paracetamol Was Effective In Reducing Pain During Local Anesthetic Administration. Also, Both Ibuprofen And Paracetamol Were Potent And Effective In Reducing Pain Following Dental Extractions After Third, Fourth, Fifth, Sixth And 24th Hours, And There Was No Difference Between Them.