NANOBONE FOR MANAGEMENT OF PERIODONTAL INTRABONY DEFECTS: A CLINICAL TRIAL

Alaa Ashraf, Weam A. El Battawy, Dina Ahmed And Noha A. Ghallab,

ABSTRACT

Objectives: This Study Was Meant To Assess Clinically The Possible Predictable Results Regarding The Use Of Nanocrystalline Hydroxyapatite Bone Graft Substitute Together With Papilla Preservation Flap Versus Papilla Preservation Flap Alone In The Treatment Of Periodontal Intrabony DefectMethods: Twenty Four Sites In 9 Patients, Within The Age Range Of 25?50 Years, Showing Intrabony Defects Were Selected And Divided Into Intervention Group Where Papilla Preservation Flap(PPF) Technique Was Performed Whether Modified(MPPF) Or Simplified(SPPF) With The Application Of Nanocrystalline Hydroxyapatite Bone Graft Substitute (PPF + N-HA) And Control Group: Where PPF Technique Alone Was Performed (MPPF Or SPPF). All The Selected Sites Were Assessed With The Clinical And Radiographic Parameters Such As Plaque Index, Gingival Index, Probing Pocket Depth And Clinical Attachment Level. All The Clinical Parameter Values Obtained At Different Intervals (baseline, 3, And 6 Months) Were Subjected To Statistical Analysis.

Results: In The Present Study, Both Groups Showed A Statistically Significantreduction In PPD And Gain In CAL, 3 And 6 Months Postoperatively Compared To Baseline Values As Well As From 3 To 6 Months Without Any Significantdifference When Compared To Each Other. The PPF+n-HA Group Demonstrated PPD Reduction Of 2.33 (?0.98) Mm After 3 Months And 3.67 (?1.07) Mm At 6 Months, While CAL Gain Reported Were 2.08 (?1.08)mm And 3.33 (?0.89) Mm At 3 And 6 Months Respectively. Concerning PPF Group, The PPD Reduction Observed Was 2.08 (?1.0) Mm At 3 Months And 3.58 (?1.31) Mm At 6 Months With A Corresponding Gain In CAL Of 1.25 (?0.97) Mm And 2.67 (?1.3) Mm Respectively. Conclusion: Both N-HA And PPFs Only Provided Significantimprovement In Clinical Outcomes After 6 Months, Yet No Significant Diferences Were Detected Between Them. Clinical Relevance: This Trial Implied That Both Modalities Were Effective In Management Of Intrabony Defects In Patients With Periodontal Diseases Associated With Deep Intrabony Defects.

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