EFFECT OF ADDITION OF NANOBIOACTIVE GLASS TO RESIN MODIFIED GLASS IONOMER IN TERMS OF SOLUBILITY, IONS RELEASE AND BIOACTIVITY

Mennat-Allah Sayed Gaber, Shaymaa I. Habib And Abdel-Hadi Mohamed Amin,

ABSTRACT


Purpose: The Aim Of This Study Was To Evaluate Solubility, Calcium And Phosphorus Ions Release And Bioactivity Of Resin Modified Glass Ionomer Cement Before And After Addition Of Nanobioactive Glass Particles.

Materials and Methods: One Commercially Available Resin Modified Glass Ionomer Cement And Nanobioactive Glass Particles Were Used In This Study. Bioactive Glass Was Added To The Cement Powder By Two Weight Percentages 2wt% And 5wt%. Solubility Was Evaluated Using ANSI/ADA Specification No.66-1989 For Glass Ionomer Cements. Twenty One Samples (n=7/gp) Were Prepared Using Split Teflon Mold (7.75�1.5mm). Solubility Was Recorded At 7 Days And 30 Days. For Calcium And Phosphorus Ions Release, 21 Samples (n=7/gp) Were Prepared Using The Same Mold And Stored In Deionized Water Then Recorded At 7 Days And 30 Days. Regarding Bioactivity ,12 Samples (n=4/gp) Were Prepared And Immersed In PBS Solution For 7 Days And 30 Days And Examined By Scanning Electron Microscope (Field Emission Gun) Attached With Energy Dispersive X-ray Analysis Unit EDXA. The Results Were Statistically Analyzed.

Results: Regarding Solubility, Results Showed A Statistically Significant Difference Between Group I, Group II And Group III After Both 7 Days And 30 Days. Moreover, Storage For 30 Days Showed Statistically Higher Solubility Values In All Groups Than 7 Days. Regarding Calcium Ions Release, There Was A Statistically Significant Difference Between Group I, Group II And Group III After Both 7 Days And 30 Days. However, No Statistically Significant Difference Was Recorded Between 7days And 30 Days In All Groups. For Phosphorus Ions Release, It Was Found That There Was A Statistically Significant Difference Between Group I, Group II And Group III After 7 Days. However, After 30 Days There Was No Statistically Significant Difference Between Group I, Group II And Group III. Results Also Showed Statistically Significant Higher Ph Ions Release After 30 Days Than 7 Days. Regarding Bioactivity, CaP Deposits Were Obvious Only In High Concentrations Of BAG (group III) After 30 Days Immersion In PBS On The Surface Of The Samples With Ca/P Molar Ratio =1.3.

Conclusions: 1. There Is A Direct Relationship Between The Amount Of BAG Added To RMGI And Its Solubility. 2. Although Addition Of BAG To RMGI Increased The Ion Bioavailability And Solubility, The Bioactivity Was Not Sufficiently Improved.

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