Mohamed Omaia Ahmed, Maged M. Negm, Yousra M. Nashaat, Nehal N. Abdelaziz And Amal S. Othman,

ABSTRACT
Background: The Elimination Of Intracanal Microorganisms Is Essential For The Long-term Success Of Root Canal Treatment. This May Be Achieved By Mechanical Cleaning And Shaping In Conjunction With Irrigation And Antibacterial Agents. The Aim Of This Study Was To Assess The Ability Of Triple Antibiotic Paste With Diclofenac Potassium Anti-inflammatory Drug Versus Calcium Hydroxide Used As Intra-canal Medication In Reducing Intracanal Bacterial Count. Methods: 84 Patients With Asymptomatic Uniradicular Necrotic Teeth Were Randomly Assigned Into Two Groups According To The Intra-canal Medication Used: Calcium Hydroxide Group (CH) And Triple Antibiotic Paste With Diclofenac Potassium Anti-inflammatory Drug Group (TAPC). After Isolation, Access Cavity Was Performed Followed By Chemo-mechanical Preparation Using Rotary Protaper Universal Files With Saline Irrigation. Bacteriological Samples Obtained From The Root Canals Before (S1) And After Instrumentation (S2) In The First Treatment Session. Subsequently, Intra-canal Medication Was Placed And Bacterial Reduction Was Assessed In The Second Session After 3 Days (S3) Using Colony Forming Unit Test.

Results: Both Intracanal Medicaments Showed A Statistically Significant Bacterial Count Reduction From S2 To S3. TAP+Catafast Intracanal Medication Achieved Significant Bacterial Count Reduction Compared To That Of Ca(OH)2. Conclusion: The Use Of Triple Antibiotic Paste With Diclofenac Potassium Anti-inflammatory Drug As Intracanal Medication Was More Effective Than That Of Calcium Hydroxide In Asymptomatic Uniradicular Necrotic Teeth.