Ali Youssef Elgendy, Ehab Elsayed Hassanien, Abeer A. Elhakim Elgendy And Elham Ibrahim Elshaboury,
ABSTRACT
Aim: This Study Aims To Evaluate Tech Biosealer Endo In Comparison With MTA Fillapex And AH Plus Regarding Biocompatibility By Means Of Histochemical Analysis.
Materials and Methods: Tech Biosealer Endo, AH Plus, And MTA Fillapex Were Placed In Polyethylene Tubes And Implanted Into The Dorsum Of Twenty-four Albino Rats. Tissues Biopsies Were Prepared For Histochemical Analysis And Evaluated At One Week, One Month And Two Month Observation Periods After The Implantation Procedure.
Results: AH Plus Presented The Highest Mean Mast Cell Count In All Observation Periods. This Was Followed By Tech Biosealer Endo And MTA Fillapex. The Empty Implanted Polyethylene Tube Showed The Least Mean Mast Cell Count. Mast Cell Degranulation Was Most Noted At The One Week And One Month Observation Periods.
Conclusion: It Can Be Concluded That Although The Subcutaneous Tissue Reactions Analyzed In The Present Study Do Not Fully Imitate Those In Root Canals And Periapical Tissues, They Are Valid In That They Comprise A Preliminary Stage In Evaluating The Biocompatibility Of The Tested Root Canal Sealers. All Implanted Sealers Induced Mast Cell Activation And Degranulation.