EVALUATION OF PLASMA RICH IN GROWTH FACTORS PRGF INJECTION FOLLOWING ARTHROCENTESIS VERSUS ARTHROCENTESIS ALONE IN TREATMENT OF TEMPOROMANDIBULAR JOINT DISC DISPLACEMENT (RANDOMIZED BLINDED CONTROLLED CLINICAL TRIAL)

Moteea Abdulsalam Ahmed Sanad , Basma Gamal Mousa And Khaled Amr,

ABSTRACT
Temporomandibular Joint TMJ Disorders TMDs Is A Umbrella Term For A Variety Of Conditions Of The Joint And Mastication Muscles. TMJ Arthrocentesis And Intra-articular Injection Are Commonly Known And Used As Minimally Invasive Surgical Treatment Of Tmj Disc Displacement With Reduction. Aim Of The Study: To Compare Between Arthrocentesis Followed By Intra Articular Injection With Plasma Rich In Growth Factors PRGF Versus Arthrocentesis Alone. Patients And Methods: Sixteen Patients Diagnosed With Anterior Disc Displacement (ADD) Were Divided Into; Intervention And Comparative Group. Clinical Outcome Parameters Were Assessed At Baseline And At 6, 12, 18 And 30 Weeks Postoperatively.

Results: Both Groups Showed Significant Improvement Of Pain And Mouth Opening, The Evaluated Parameters Showed Insignificant Differences Between The Two Groups Throughout The Study Intervals With The Exception That The PRGF Group Showed Statistically Significant Pain Reduction And Mouth Opening Improvement In 30 And 6 Weeks Postoperative Respectively (p = 0.01 , 0.03) Conclusion: Both TMJ Arthrocentesis With Intra-articular Injection Of PRGF Or Arthrocentesis Only Was Proved To Reduce Symptoms Of Pain And Limited Mouth Opening And To Maintain Improvements Over Time. PRGF Injection After Arthrocentesis Revealed Some Superiority In Pain Reduction And Mouth Opening Over Arthrocentesis In 30, 6 Weeks Interval Respectively.

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