Reem Ahmed Hany, Shaymaa I. Habib And Gihan Ali Abdelrahman,

ABSTRACT





Purpose: The Aim Of This Study Was To Evaluate The Antifungal Effect Of Immersed Acrylic Resin Material In Aqueous Extract Of Siwak Solution On Candida Albicans In Comparison To Distilled Water As A Negative Control Or Sodium Hypochlorite As A Positive Control.

Materials And

Methods: One Commercially Available Heat Cured Acrylic Resin; Aqueous Extract Of Siwak And 0.5% Sodium Hypochlorite Were Used In This Study. For Antifungal Evaluation, The Assessment Was Done By Two Techniques; Agar Diffusion Method And Agar Dilution Method. Twenty Seven Specimens (n=9/gp) Were Prepared Using Split Teflon Mold (4�4 Mm) For Each Test. The Specimens Were Randomly Assigned Into Three Groups According To The Type Of The Immersion Solution. Group (I) Aqueous Extract Of Siwak Solution, Group (II) Distilled Water And Group (III) 0.5% Sodium Hypochlorite. The Results Were Statistically Analyzed.



Results: Regarding The Agar Diffusion Method, A Statistically Significant Difference Was Found Between The Antifungal Activities Of The Three Groups. The Highest Mean Antifungal Activity Was Recorded For Group I, Followed By Group III. While The Least Mean Value Was Recorded For Group II. Regarding The Agar Dilution Method In Both Concentrations (1/100 And 1/10), There Was A Statistically Significant Difference Between The Three Investigated Groups. The Highest Candida Count In Colony Forming Units (CFU) Was Recorded For Group II. Meanwhile, The Least Candida Count Was Recorded For Group I. While There Was No Significant Difference Between Group III And Group I.



Conclusions: 1) The Aqueous Extract Of Siwak As A Denture Immersion Solution Has A Potent Antifungal Activity On Candida Albicans. 2) The Aqueous Extract Of Siwak Can Be Safely Applied In Everyday Practice For The Acrylic Dentures Disinfection.