Raghda Ashraf Hassan Fayez, Ahmed Nour-Eldin Ahmed Habiband Rasha Mohamed Abdelraouf,

ABSTRACT

Objectives: The Aim Of The Present Study Is To Evaluate The Effect Of An Experimental Bioactive Glass-based Nanopowder Formula (BG-based Formula) Compared To Casein Phosphopeptide-Amorphous Calcium Phosphate Fluoride (CPP-ACPF) On Remineralization Of Experimentally Induced White Spot Lesions (WSL) In Enamel. Methods: Twenty Seven Upper Human Permanent Central Incisors Were Collected, Polished And Randomly Distributed Into Three Groups (I, II And III). WSLs Were Induced In All Teeth. Each Group Was Daily Subjected To The Remineralizing Agents (14 Days); Group I (negative Control) Was Suspended In Artificial Saliva, Group II Was Treated With CPP-ACPF, While Group III Was Treated With The Slurry Of The Experimental BG-based Formula. The Microstructure And Minerals Content Of Enamel Were Examined For Each Group Using SEM And EDXA At The Baseline, After Formation Of The WSL, And After Remineralization.

Results: Group III (the Experimental BG-based Formula) Showed More Regular Deposition Of The Mineral Layer On The Surface. A Subsurface EDXA Profile Of A Sectioned Representative Tooth From Each Group Showed That The Experimental BG-based Formula Was Effective In Surface As Well As Subsurface Remineralization Of WSLs. Whereas, MI GC Tooth Paste Plus (CPP-ACPF) Showed Remineralization Of The Enamel Subsurface More Than The Enamel Surface. Significance: Both CPP-ACPF And The New Experimental BG-based Nanopowder Formula Were Both Effective In Remineralization Of Enamel WSLs, With Less Surface Remineralization In Case Of CPP-ACPF.