Ahmed Hamed Gouda Shemis , Hamida Refai Hassanien And Osama Taema,

ABSTRACT
The Aim Of This Study Was To Assess The Efficacy Of Autologous Platelet-rich Plasma (PRP) Compared With Dextrose Prolotherapy (DP) In Patients With TMJ Hypermobility. Subjects And Methods: Forty Two Patients With Symptomatic TMJ Hypermobility Were Included In This Study. They Were 7 Male And 35 Females. Their Ages Ranged From 18-48 Years, With An Average Of 30.69 � 8.67 Years. After Accepting To Be Enrolled In The Present Study, The Participants Were Randomly Assigned Into One Of Two Equal Groups Using A Computer-generated Randomization Schedule. In PRP Group, Each TMJ Received 2 Sessions Of Intra-articular And Pericapsular Injections With 1.5 Ml Of PRP With 2 Weeks Apart. While In Dextrose Group, Each TMJ Received 4 Sessions Of Intra-articular And Pericapsular Injections With A Dextrose Solution Of 2ml Of 10% Dextrose And 1ml Of 2% Mepivacaine With Six Weeks Apart Both The Assessor And The Statistician Regarding The Group Allocation.

Results: The Outcome Measures Were Assessed And Documented At Baseline And At 2, 6, 12, 18 And 30 Weeks After Treatment. They Include Assessment Of The Patient?s Subjective Pain On Function According To The Visual Analog Scale (VAS), Frequency Of Luxations, MMO And Clicking Sound. By The End Both Groups Showed Statistically Significant Decrease In All The Evaluated Parameters At 2 Weeks After Treatment That Maintained Thereafter. Comparing The Two Groups Revealed Significant Reduction Of TMJ Pain And MMO In PRP Group Than Dextrose Group.