THE EFFECTIVENESS OF CHITOSAN COLLAGEN MEMBRANE WITH AND WITHOUT HYDROXYAPATITE PARTICLES IN THE TREATMENT OF CLASS II MANDIBULAR FURCATION DEFECTS IN HUMANS: A RANDOMIZED CLINICAL AND RADIOGRAPHIC EVALUATION

Mohammed Omar El Borae , Samia A. Darwish, Mona Yehia Abd El Razzak And Hussein Ibrahim Saudi,

ABSTRACT

Objectives: The Present Study Evaluated Clinically And Radiographically The Efficacy Of Chitosan Collagen Membrane With And Without Nanohydroxyapatite Particles, Versus Collagen Or Chitosan Membrane With Nanohydroxyapatite Bone Graft, In The Treatment Of Class II Mandibular Furcation Defects.

Materials and Methods: Forty Intrabony Periodontal Defects In 13 Patients With Mandibular Grade II Furcation Involvement Were Selected According To The Criteria Outlined By Presence Of Class II Furcation Defects With �3 Mm Horizontal Probing Depth, Clinical Attachment Level (CAL) � 5 Mm. The Defects Were Treated With Collagen Membrane Plus Chitosan Mixed Together As One Membrane With Nanohydroxyapatite Particles On Its Surface (c/ch/OH) M As Group 1, Collagen Membrane Plus Chitosan Mixed Together As One Membrane (c/ch) M As Group 2, Nanohydroxyapatite Bone Graft With Collagen Membrane (OH/c) G+m As Group 3, Nanohydroxyapatite Bone Graft With Chitosan Membrane ( OH/ch) G+m As Group 4. The Following Clinical Parameters Were Recorded: PI PD, CAL And BOP At Baseline, 6 & 12 Months Post Therapy And Furcation Assessment (F) At Baseline & 12 Months Post Therapy. CBCT And Standardized Periapical Radiographs Were Taken At Baseline & 12 Months Post-surgery. The Collected Data Was Statistically Analyzed At The Different Follow Up Periods. Clinical

Results: The Results Of The Present Study Showed Significant Reduction Of PD, CAL, BOP And F In All Study Groups Along Different Study Periods With No Significant Difference Between Groups. The Radiographic Results Of The Present Study Showed Significant Reduction Of D, H, W And 3D Using CBCT In All Study Groups Along Different Study Periods With No Significant Difference Between Groups.

Conclusions:Based On The Results Of The Current Study, It Could Be Concluded That, The Combination Of Chitosan With Nanohydroxyapatite, Whether Applied Into The Furcation Itself As A Bone Graft (group 4) Or Incorporated With The Membrane (group 1) Had A Potentiating Effect On The Clinical And Radiographic Outcomes.

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