Walaa Kadry, Mervat El Deftar, Yasmine Nassar And Maha M Hakam,

ABSTRACT
Aim Of The Study: To Clinically And Radiographically (as Regards Bone Density) Assess The Outcomes Of Unilateral Alveolar Clefts Grafted With Tissue Engineered Constructs. Patients And Methods: This Study Was Conducted On Five Patients Presented With Unilateral Alveolar Clefts And Indicated For Secondary Alveolar Bone Grafting. The Alveolar Clefts Were Grafted With Tissue Engineered Constructs Composed Of Osteogenically Differentiated Mesenchymal Stem Cells (MSCs) Derived From The Patient�s Bone Marrow And Loaded On Collagen Scaffolds (Osteovit). Postoperative Clinical Follow-up And A Radiographic 6 Months Postoperative Follow-up Using CT Scan Was Performed At 6 Months Follow Up Period. The Newly Formed Bone Density Was Measured From The CT Scans And Compared To The Native Bone Density On Axial CT Scans.

Results: The Newly Formed Bone Density Was (312.84 HU) Compared To The Native Bone (495.39 HU).