Eslam Said Mohamed, Ragia Mohamed Mounir, Nadia Galal Mohamedand Maha Mohamed Sallam,

ABSTRACT
Objective: To Evaluate The Effect Of Using Simvastatin On Bone Osseointegration Surrounding Dental Implants. Methodology: Twelve Implants That Were Inserted And Divied Into 2 Equal Groups, Each Group Contained Six Implants (simvastatin Group And Control Group). All Implants Were Done Using Delayed Submerged Implant Insertion Technique. Group One Received Simvastatin Powder As An Adjunctive; To Improve The Osseoientgration Of The Bone Surrounding The Dental Implants, While Group Two With No Adjunctive. All Patients Were Followed Up Clinically And Radiographically For Osseointegration Using Cone Beam CT Two Months, And Six Month Postoperatively.

Results: Simvastatin Group Showed Statistically Low Significant Increase In The Percentage Of Increase In The Mean Bone Density, When Compared To The Control Group. Moreover, It Showed Statistically Low Significant Decrease In The Bone Height Loss Than The Control Group. Conclusion: Simvastatin Powder Is A Safe, Efficient And Easy Way For Mild Acceleration Of Bone Healing And Osseointegration Surrounding Titanium Dental Implants. The Simvastatin Drug Has The Main Function As Antihypercholaesterlemia Drug In Addition To Its Ostegeonic Effect On Bone.