Farah Anas, Manar Fouda And Shaimaa Ismail Gawdat,

ABSTRACT


Introduction: This Study Was Designed As A Prospective, Randomized, Double-blind Clinical Trial To Evaluate The Efficacy Of 2% Mepivacaine With 1:100,000 Epinephrine Versus 4% Articaine With 1:100,000 Epinephrine For Inferior Alveolar Nerve Block (IANB) In Patients With Symptomatic Irreversible Pulpitis In Mandibular Molars. Participants And Methods: Sixty Six Patients Diagnosed With Symptomatic Irreversible Pulpitis In Mandibular Molar Teeth Randomly Received 3.6 ML Of 2% Mepivacaine (2 Carpules) Or 3.4 ML Of 4% Articaine (2 Carpules) Both With 1:100,000 Epinephrine, Using A Conventional IANB Technique. Subject?s Self-reported Pain Response Was Recorded On Numerical Rating Scale (NRS) After Local Anesthetic Administration During Access Preparation And Instrumentation.

Results: For Statistical Analysis The Collected Data Were Subjected To Independent T-test, Chi-square And Fisher?s Exact Showed No Significant Difference In Success Rates Between The Two Groups(P<0.05). Conclusion: For Mandibular Molars With Symptomatic Irreversible Pulpitis The Anesthetic Efficacy Was Similar For Both Mepivacaine And Articaine, And Neither Solution Resulted In Complete Pulpal Anesthesia And Both Groups Showed High Rate Of Need For Supplemental Anesthesia To Control Pain During Treatment.