Asmaa Abou-Bakr, Nevine H. Kheir El Din, Eman Khalil And Radwa R. Hussein,

ABSTRACT
Chronic Kidney Failure (CRF) Is Becoming A Major Public Health Problem Worldwide Particularly In Developed Countries With A Higher Prevalence Of Renal Disease. Hemodialysis Is The Most Widely Used Treatment Of Nephropathy. Both The Disease And The Treatment Can Inflict Respiratory, Endocrine And Immunological Complications, Which Could Influence The Patient?s Oral Status As Well As Alterations In Salivary Flow And Salivary PH. There Are Guidelines For Oral Health Care In Patients With Systemic Diseases; Additionally, A Significant Improvement In The Underlying Systemic Diseases Has Been Reported Following Treatment Of The Associated Oral Lesions

Materials and Methods: 114 Patients Of Each Gender With Age Vary From 30 To 60 Years Diagnosed With End-stage Renal Disease Undergoing Hemodialysis From Six Months Up To Two Years Were Involved In This Study From The Nephrology Department At Benha University. Patients With A History Of Any Serious Sickness As Malignancy Or Who Undergo Kidney Transplants Or Those That Take Medication That Would Cause Oral Manifestations As Steroids And Smokers Were Excluded In Our Study. Oral Examinations Were Done According To The Modified WHO Oral Health Survey 2013 Criteria. Saliva Was Collected Once Pre-stimulation To Measure The Rate Of Flow And PH.

Results: Oral Changes Were Present In All 114 (100%) CRF Patients. Chronic Periodontitis Was The Most Frequently Seen Disease In (81.6%) CRF Patients. Alternative Findings Were Xerostomia, Burning Mouth, Uremic Breath, Petechial Lesions, Pallor, And Abnormal Pigmentation. In Our Study, We Found An Association Between Xerostomia And Salivary Flow Rate. We Also Found That Patients With Lip Pigmentation Showed Statistically Significantly Low Mean Blood Urea Levels. Conclusion: Many Alterations In The Oral And Salivary Parameters Were Found At The CRF Patients. These Patients Need Special Attention Towards Their Dental Treatment, Not Only Because Of The Disease Itself And Its Multiple Oral Manifestations But Also Because Of The Side-effects And Characteristics Of The Treatments They Receive. The Greater Predominance Of Oral Lesions In CRF Patients Imposes Mandatory Oral Screening To Recognize Patients At Risk. The Management Of Such Will Enhance The Overall Well-being Of CRF Patients In Developed Countries.

Asmaa Mahmoud Abdeen, Tarik Essawy And Saher Sayed Mohammed,

ABSTRACT
Background: Sofosbuvir (SOF) Was Published In 2013 As A Part Of First-linetreatment For Hepatitis C Virus (HCV) By The American Association For The Study Of Liver Diseases . SOF Was Recommended For All Genotypes With A Cure Rate Greater Than 90%. Objective: Investigating Sofosbuvir-induced Alterations In The Rat Submandibular Salivary Gland (SMSG) Histologically And Immunohistochemically. Methodology: 80 Adult Rats Weighing About ?150 Gm Were Divided Into 2 Groups, Group I (control Group) And Group II (experimental Group) Divided In To 3 Subgroups And Received SOF 40 Mg/kg/day For 1, 2 And 3 Months. All Animals Were Sacrificed,SMSG Were Dissected And Specimens Were Examined Histologically And Immunohistochemically.

Results: Compared To Group I, Group II Subgroup (1) And (2) Showed Acinar And Ductal Vacuolization, Oedema, Discontinuity Of The Epithelial Lining With Retained Coagulum In The Granular Convoluted Tubules (GCTs). These Changes Were Found To Be Exaggerated In Subgroup (3) Accompanied By Acinar And Ductal Shrinkage And Loss Of Gland Compactness. A Statistically Highly Significantdecrease In PCNA Immunoreaction Was Noticed In Experimental Group From Subgroup (1) To Subgroup (3). Conclusion: SOF Had Affected The Structure And Function Of SMSG Through Increased Reactive Oxygen Species (ROS) Levels Leading To Degenerative Changes.

Asmaa R. Latif, Dina F. Ahmed And Mohamed K. Zayet,

ABSTRACT
Objective: The Aim Of This Study Was To Reveal The Effect Of Using Ultra-low Dose Protocol Of Planmeca ProMax 3D Mid Cone Beam Computed Tomography (CBCT) Scanner On The Identification Of Anatomical Landmarks For Pre-operative Implant Planning. Subjects And Methods: Thirty Two CBCT Scans For 27 Patients Were Taken Using Planmeca ProMax 3D Mid Scanner. Half Of The Scans Were Taken With The Manufacturer?s Recommended Exposure Parameters (standard Protocol) And The Other Half Were Taken With The Ultra-low Dose Protocol. Identification Of Nine Maxillary And Mandibular Anatomical Landmarks By Three Observers Was Performed According To Four-point Scale. Additionally, Intra-observer And Inter-observer Agreement Were Performed.

Results: Statistical Analysis Revealed That The Results Of The Ultra-low Dose Protocol Were Comparable To That Of The Manufacturer?s Recommended Exposure Parameters. The Average Mean Value Of The Total Identified Anatomical Landmarks Using Ultra-low Dose Protocol Was Almost The Same As That Of The Manufacturer?s Recommended Exposure Parameters. The Approximated Average Mean Value Was 3.55 In Both Protocols. The Intra-observer And Inter-observer Agreement Ranged From Substantial To Excellent.

Conclusions: Images Taken By Ultra-low Dose Protocol Of Planmeca Promax 3D Mid CBCT Scanner Have The Same Degree Of Appropriateness In Identification Of Implant-related Anatomical Landmarks When Compared With Those Taken With Manufacturer?s Recommended Dose.

Asmaa Mamdouh Mohamed, Mohamed ElHadidy, Atef Fouda And Dina Mohamed Elbeshlawy,

ABSTRACT


Aim: Evaluation Of Socket Preservation Using Hydroxyapatite With Non-Resorbable Polytet-rafluoroethylenemembrane (Cytoplast Membrane) Versus Non-resorbable Polytetrafluoroethylenemembrane (Cytoplast Membrane) Only In Mandibular 1st Or 2nd Molar Sockets.Patients And Methods: The Present Study Was Conducted On 20 Cases Seeking Extraction Of Lower Firstor Second Molars. Patients Are Divided Into 2 Groups, Preservation Of The Extracted Sockets By Alloplastic Materials And Non-resorbable Membrane Was Done In Study Group And Preservation Of The Extracted Sockets By Non-resorbable Membrane Only Was Done In Control Group. All Extraction Sockets Were Assessed Postoperatively Immediately After Extraction, At 3 And 6 Months Intervals For Evaluation Of The Variation In The Bone Density At The Extraction Site Of Both Groups.

Results: The Bone Density Was Compared Between The Study And Control Groups At The Crestal, Middle And Apical Parts Of The Distal And Mesial Roots Immediate, At 3 Month And At 6 Month Post Operatively. Study Group Showed Mean Density Higher Than The Control Group And The Difference Was Statistically Significant For All IntervalsConclusion: The Bone Density In Sockets With Hydroxyapatite Is Higher Than The Sockets Which Are Covered With Cytoplast Membrane Only.

Sarah M. El-Ayoutti, Basma G Moussa, Omniya A. Aziz And Mamdouh A. Hassan,

ABSTRACT
The Aim Of This Study Was To Assess The Incidence Of Fistula In Isolated Cleft Palate Patients Repaired By Furlow Double-opposing Z-plasty Versus Two-flap Palatoplasty At Different Follow-up Periods. One Case Of The Furlow Group Showed Fistula Formation. However, Three Cases Had Nasal Regurgitation Only In The Two Flap Group. Amount Of Intra-operative Blood Loss Was Significant In The Furlow Group; It Was Mostly Related To The Extent Of The Surgical Field And Time Of Surgery.

Abdullah AbdelBaky AlAfifi , Asmaa Yassen And Olfat Hassanein,

ABSTRACT

Objectives: Microhardness Evaluation Of Initial Enamel Lesions By Bioactive Glass Air-abrasion Before NovaMin Application. Methods: 40 Extracted Human Molars Were Sectioned Mesiodistally And Were Embedded In Resin Molds. Specimens Were Assigned To 4 Groups According To The Remineralization Protocol: G1- (artificial Saliva), G2- (air-abrasion), G3- (NovaMin), G4- (air-abrasion + NovaMin). Specimens Were Immersed In A Daily Renewed Demineralizing Solution To Create Artificial White Spot Lesions. Specimens Were Stored In A Daily Renewed Artificial Saliva. Microhardness Was Assessed Using Vicker?s Hardness Number (VHN) At Starting Point, After Demineralization, After 24 Hours And One Month Remineralization.

Results: The Group Of Air-abrasion That Received NovaMin For One Month Showed The Highest Statistically Significant VHN, With No Statistically Significant Difference Between The VHN Values Of This Group After Remineralization And At Starting Point.

Conclusions: Air-abrasion Of Enamel With Bioactive Glass Did Not Play A Role To Improve Remineralization.

Asmaa Yousry Tawfiq, Hoda Abdel Kader Saleh And Salma Belal Eiid,

ABSTRACT


Purpose: To Investigate The Diagnostic Accuracy Of Ultra Low Dose-Cone Beam Computed Tomography Protocol In Detection Of External Root Resorption In Mandibular Teeth.

Materials and Methods: Twenty Extracted Human Mandibular Intact Roots Were Recruited In This In-vitro Diagnostic Study. Simulated Resorptive Defects Of Various Standardized Sizes (0.5mm-0.9mm-1mm) Were Drilled On Each Root Using Inverted Cone Burs With Different Sizes Mounted On Low Speed Hand-piece. Some Sites Were Left Intact On Each Root To Act As Control Sites. The Total Number Of Simulated Defects Was 180 Distributed Randomly On Different Root Surfaces, While A Total Of 60 Sites Were Left Intact. Prepared Roots Were Fitted Into Corresponding Sockets Of A Mandible To Be Scanned By Ultra Low Dose-Cone Beam Computed Tomography Protocol (90 Kvp, 5.6 MA, 4 Seconds) Using A 0.2 Mm Voxel Size And A Field Of View 4x5 Cm .

Results: Ultra Low Dose-Cone Beam Computed Tomography Protocol Had An Overall Sensitivity Of (71%), And Overall Specificity Of (96%). The Diagnostic Accuracy In This In Vitro Study Was (77%). The Positive Predictive Value Recorded Was (98%), While The Negative Predictive Value Was (52%). The Positive Likelihood Ratio Was (18) And The Negative Likelihood Ratio Was (0.3). Conclusion: Ultra Low Dose-Cone Beam Computed Tomography Protocol Could Be Used For Detection Of External Root Resorption With Comparable Diagnostic Accuracy To Standard Protocols But With Significantly Less Radiation Dose.

Asmaa A.Desouky, Maged M. Negm And Magdy M.M. Ali,

ABSTRACT
Objectives The Aim Of This Article Is To Evaluate The Sealability Of Experimental Nanosealers (nano Calcium Hydroxide And Nano Bioactive Glass) And To Compare It With The Commercial Zinc Oxide Eugenol Sealer. Methodology Sixty Single-root Human Mandibular Premolars Were Selected And Instrumented With Protaper Ni-Ti Rotary File And The Final File Size Was Up To # F4/.06. They Were Then Randomly Allocated Into 3 Groups, And All Samples Were Filled With Single Cone Gutta-percha (#40/06) And One Of The Tested Sealers. All Specimens Were Tested By Dye Penetration Test To Evaluate The Sealability Of Newly Introduced Nanosealers. Results Significant Improvement Shown By The Presented Study Suggests That Nano Calcium Hydroxide Sealer Showed Significantly Less Dye Leakage Than Nano Bioactive Glass Sealer And Zinc Oxide Eugenol Sealer. Conclusions The Results Of This Study Showed That The Synthesized Nano-powder Sealers Are Suitable For Use In Root Canal Therapy To Prevent Leakage.

Asmaa Abubakr Rashed And Ali Ibrahim Abdalla,

ABSTRACT
Aims: The Objective Of This Study Was To Evaluate One-year Clinical Performance Of Composite Veneers Applied With Different Techniques.Methods And Material: This Study Was Conducted As A Modifiedrandomized Split-mouth Design On Site Level, Where The Two Groupes Composite Veneer Techniques Under Investigation Were Randomly Assigned To Either The Right Or Left Upper Anterior Teeth. The (group I) 16 Teeth Were Restored With A Prefabricated Composite Veneer System COMPONEER(COLTEEN), While (group II) 16 Teeth Were Restored With Free Hand Layering Direct Approach With IPS EMPRESS DIRECT (Ivoclar) Assisted With Preformed Template U-VENEER (Ultradent). At Baseline, 6 And 12 Months, The Restorations Were Evaluated Using ModifiedUSBHS Criteria For Marginal Discoloration, Recurrent Caries And Post Operative Hypersenstivity.Statistical Analysis Used: The Recorded Data At The Different Follow Up Periods Were Collected, Tabulated And Statistically Analyzed Using SPSS (Statistical Package For The Social Sciences) Software Version 25.0.

Results: Regarding The All Evaluation Criteria, Were No Statistically Significantlydifferent Between The Two Groups At The End Of Evaluation Period (p?0.05).

Conclusions: The Acceptable Clinical Performance Of Both Composite Veneer Techniques With Only Minor Changes Had Been Recorded Between Baseline And The Follow-up Evaluation At 12 Months.

Basma Gamal Hassan, Omaima Mohamed Safwat, Mohsen Hussein Abi Al Hassanand Noha Saleh M. Abu-Taleb,

ABSTRACT


Aim: This Study Was Conducted To Evaluate And Compare The Thickness Of Calcificbridge Formed By Indirect Pulp Capping Using Light Activated Calcium Silicate Versus Light Activated Calcium Hydroxide, Immediately After Restoration And One Year Later Using Digital Radiography.Methodology: 30 Participants Were Recruited In This Study For Having 60 Molars With Deep Occlusal Carious Lesions. Molars Of Each Patient Were Randomly Divided Into Two Groups Treated With Partial Caries Removal Technique The Firstgroup Represented Teeth Treated With Application Of Light Activated Calcium Silicate (TheraCal) Prior To Finalpermanent Resin Composite Restoration, The Second Group (comparator Group) Represented Teeth Treated With Light Activated Calcium Hydroxide. Radiographic Images Were Obtained And Radiographic Dentin Bridge Thicknesses Were Evaluated Using Digora For Windows Computer Software At Baseline Immediately After Restoration And After One Year.

Results: The Formed Dentin Bridge Thickness Was Thicker In The Calcium Hydroxide Group Than Calcium Silicate Group (0.24%mm And 0.16%mm Respectively) And The Percentage Of Change In Dentin Bridge Thickness After One Year Was Thicker In Calcium Hydroxide Group Than Calcium Silicate (TheraCal) Group (24% And 16.26% Respectively).

Conclusions: Calcium Hydroxide Is Still Effective As A Pulp Capping Material Compared To Resin Modified Calcium Silicate