Asmaa Abou-Bakr, Nevine H. Kheir El Din, Eman Khalil And Radwa R. Hussein,
ABSTRACT
Chronic Kidney Failure (CRF) Is Becoming A Major Public Health Problem Worldwide Particularly In Developed Countries With A Higher Prevalence Of Renal Disease. Hemodialysis Is The Most Widely Used Treatment Of Nephropathy. Both The Disease And The Treatment Can Inflict Respiratory, Endocrine And Immunological Complications, Which Could Influence The Patient?s Oral Status As Well As Alterations In Salivary Flow And Salivary PH. There Are Guidelines For Oral Health Care In Patients With Systemic Diseases; Additionally, A Significant Improvement In The Underlying Systemic Diseases Has Been Reported Following Treatment Of The Associated Oral Lesions
Materials and Methods: 114 Patients Of Each Gender With Age Vary From 30 To 60 Years Diagnosed With End-stage Renal Disease Undergoing Hemodialysis From Six Months Up To Two Years Were Involved In This Study From The Nephrology Department At Benha University. Patients With A History Of Any Serious Sickness As Malignancy Or Who Undergo Kidney Transplants Or Those That Take Medication That Would Cause Oral Manifestations As Steroids And Smokers Were Excluded In Our Study. Oral Examinations Were Done According To The Modified WHO Oral Health Survey 2013 Criteria. Saliva Was Collected Once Pre-stimulation To Measure The Rate Of Flow And PH.
Results: Oral Changes Were Present In All 114 (100%) CRF Patients. Chronic Periodontitis Was The Most Frequently Seen Disease In (81.6%) CRF Patients. Alternative Findings Were Xerostomia, Burning Mouth, Uremic Breath, Petechial Lesions, Pallor, And Abnormal Pigmentation. In Our Study, We Found An Association Between Xerostomia And Salivary Flow Rate. We Also Found That Patients With Lip Pigmentation Showed Statistically Significantly Low Mean Blood Urea Levels.
Conclusion: Many Alterations In The Oral And Salivary Parameters Were Found At The CRF Patients. These Patients Need Special Attention Towards Their Dental Treatment, Not Only Because Of The Disease Itself And Its Multiple Oral Manifestations But Also Because Of The Side-effects And Characteristics Of The Treatments They Receive. The Greater Predominance Of Oral Lesions In CRF Patients Imposes Mandatory Oral Screening To Recognize Patients At Risk. The Management Of Such Will Enhance The Overall Well-being Of CRF Patients In Developed Countries.