USE OF CLEFT MARGIN FLAP WITH ANTERIOR PALATAL CLOSURE FOR CLOSURE OF NASO-ALVEOLAR DEFECT DURING PRIMARY CLEFT LIP REPAIR (PILOT STUDY)

Dina Yacoub*, Sherif Ali*, Mamdouh Ahmed AboulHassan** And Mohamed Galal Beheiri *,

ABSTRACT
The Aim Of This Study Was To Introduce A Method For Utilizing The Lateral Cleft Marginal Fla And Evaluating Its Efficac In Closing The Naso-alveolar Defect At The Time Of The Primary Cleft Lip Repair. The Introduced Method Was Performed For 10 Patients With Non-syndromic Unilateral Complete Cleft Lip And Palate. All The Assigned Patients Were Treated By Modifie Millard Cheiloplasty With Simultaneous Anterior Palatal Closure Using The Vomerine Fla. Outcome Was Evaluated By Assessing The Wound Healing At The Alveolar Area By Clinical Examination At 1 Week And Then At 1 Month After The Surgery. Detachment Of The Fla And Unfavourable Wound Healing Was Observed In Only 10% Of The Cases Included In The Study. In Conclusion, This Method Is Reliable And Promising For Providing A Soft Tissue Closure Of The Naso-alveolar Defects At An Early Stage And Thus Appears To Improve The Quality Of Life For Such Patients.

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RADIOGRAPHIC ASSESSMENT OF CALCIFIC BRIDGE FORMATION BY LIGHT ACTIVATED CALCIUM SILICATE VERSUS LIGHT ACTIVATED CALCIUM HYDROXIDE IN MANAGEMENT OF SIMPLE DEEPLY SEATED CARIOUS LESIONS WITH PARTIAL CARIES REMOVAL: RANDOMIZED CLINICAL TRIAL

Basma Gamal Hassan, Omaima Mohamed Safwat, Mohsen Hussein Abi Al Hassanand Noha Saleh M. Abu-Taleb,

ABSTRACT


Aim: This Study Was Conducted To Evaluate And Compare The Thickness Of Calcificbridge Formed By Indirect Pulp Capping Using Light Activated Calcium Silicate Versus Light Activated Calcium Hydroxide, Immediately After Restoration And One Year Later Using Digital Radiography.Methodology: 30 Participants Were Recruited In This Study For Having 60 Molars With Deep Occlusal Carious Lesions. Molars Of Each Patient Were Randomly Divided Into Two Groups Treated With Partial Caries Removal Technique The Firstgroup Represented Teeth Treated With Application Of Light Activated Calcium Silicate (TheraCal) Prior To Finalpermanent Resin Composite Restoration, The Second Group (comparator Group) Represented Teeth Treated With Light Activated Calcium Hydroxide. Radiographic Images Were Obtained And Radiographic Dentin Bridge Thicknesses Were Evaluated Using Digora For Windows Computer Software At Baseline Immediately After Restoration And After One Year.

Results: The Formed Dentin Bridge Thickness Was Thicker In The Calcium Hydroxide Group Than Calcium Silicate Group (0.24%mm And 0.16%mm Respectively) And The Percentage Of Change In Dentin Bridge Thickness After One Year Was Thicker In Calcium Hydroxide Group Than Calcium Silicate (TheraCal) Group (24% And 16.26% Respectively).

Conclusions: Calcium Hydroxide Is Still Effective As A Pulp Capping Material Compared To Resin Modified Calcium Silicate

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NANOBONE FOR MANAGEMENT OF PERIODONTAL INTRABONY DEFECTS: A CLINICAL TRIAL

Alaa Ashraf, Weam A. El Battawy, Dina Ahmed And Noha A. Ghallab,

ABSTRACT

Objectives: This Study Was Meant To Assess Clinically The Possible Predictable Results Regarding The Use Of Nanocrystalline Hydroxyapatite Bone Graft Substitute Together With Papilla Preservation Flap Versus Papilla Preservation Flap Alone In The Treatment Of Periodontal Intrabony DefectMethods: Twenty Four Sites In 9 Patients, Within The Age Range Of 25?50 Years, Showing Intrabony Defects Were Selected And Divided Into Intervention Group Where Papilla Preservation Flap(PPF) Technique Was Performed Whether Modified(MPPF) Or Simplified(SPPF) With The Application Of Nanocrystalline Hydroxyapatite Bone Graft Substitute (PPF + N-HA) And Control Group: Where PPF Technique Alone Was Performed (MPPF Or SPPF). All The Selected Sites Were Assessed With The Clinical And Radiographic Parameters Such As Plaque Index, Gingival Index, Probing Pocket Depth And Clinical Attachment Level. All The Clinical Parameter Values Obtained At Different Intervals (baseline, 3, And 6 Months) Were Subjected To Statistical Analysis.

Results: In The Present Study, Both Groups Showed A Statistically Significantreduction In PPD And Gain In CAL, 3 And 6 Months Postoperatively Compared To Baseline Values As Well As From 3 To 6 Months Without Any Significantdifference When Compared To Each Other. The PPF+n-HA Group Demonstrated PPD Reduction Of 2.33 (?0.98) Mm After 3 Months And 3.67 (?1.07) Mm At 6 Months, While CAL Gain Reported Were 2.08 (?1.08)mm And 3.33 (?0.89) Mm At 3 And 6 Months Respectively. Concerning PPF Group, The PPD Reduction Observed Was 2.08 (?1.0) Mm At 3 Months And 3.58 (?1.31) Mm At 6 Months With A Corresponding Gain In CAL Of 1.25 (?0.97) Mm And 2.67 (?1.3) Mm Respectively. Conclusion: Both N-HA And PPFs Only Provided Significantimprovement In Clinical Outcomes After 6 Months, Yet No Significant Diferences Were Detected Between Them. Clinical Relevance: This Trial Implied That Both Modalities Were Effective In Management Of Intrabony Defects In Patients With Periodontal Diseases Associated With Deep Intrabony Defects.

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MANAGEMENT ORTHODONTIC SPACES IN AN ADULT PATIENT: A CASE REPORT

Rawda AlGhabban,

ABSTRACT
Teeth Spacing Is A Dental Abnormality Defineby Interdental Spaces And Lack Of Contact Points Between Teeth. The Appearance Of A Diastema Between The Central Incisors In Adults Often Is Considered Non-esthetic And Malocclusion Problem. Extent And The Etiology Of The Diastema And Spacing Must Be Properly Evaluated. The Author Report A Case Of 32 Years Old Female Who Presented To The Orthodontic Clinic With Moderate Upper And Lower Spacing, Anterior Diastema, And Lower Midline Shifted To Left Side By 3mm. It Was Decided To Treat The Case With Fixedorthodontic Therapy. The Spaces Were Closed Simply And Coordinate Both Arches. At The End Of The Treatment, Archived Ideal Overjet And Overbite, Pleasing Profileand An Esthetic Smile. The Present Case Study Demonstrates That Close The Spaces Orthodontically Could Be A Good Choice For Mild To Moderate Spacing Cases. The Most Important Part Of Treating Spacing Cases Is Maintenance Of Treatment Result. It Has High Relapse Tendency.

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IMMUNOHISTOCHEMICAL EXPRESSION OF CYCLOOXGYNASE-2 AND TRANSFORMING GROWTH FACTOR-?1 IN ADENOID CYSTIC CARCINOMA OF SALIVARY GLAND (IN VITRO STUDY)

Amal Mostafa Sayed, Reham Salah Hamed And Amal Hassan Abdelrahman ,

ABSTRACT
Background: ACC Has Several Distinctive Characteristics Including Multiple Local Recurrences, High Incidences Of Metastasis And Poor Prognosis. Therefore Studying Effective Markers To Predict The Risk Of Malignancy And Clarifiction Of The Underlying Molecular Mechanisms Are Essential To Understand The Clinical Behavior And Facilitate The Management Of ACC. Objective: To Investigate The Immunohistochemical Expression Of TGF-?1 And COX-2 In Different Variants Of ACC (cribriform, Tubular/trabecular And Solid) And Correlate The Expression Of The Two Markers With Each Other. Methods: A Total Of 30 Specimens Were Collected. The Standard Avidin-biotinperoxidase Technique Has Been Used In The Present Study For Detection Of TGF- ?1 And COX-2, The Immunostaining Of These Markers Were Evaluated By An Image Analyzer Computer System.

Results: COX-2 And TGF-?1expression Was Significantlyincreased In Solid Variant Of ACC Than Other Patterns And Thus Concluded That COX-2 And TGF-?1expression Are Directly Related To ACC Histopathological Grade. Also, A Significantdirect Correlation Between The Immunostaining Of TGF-?1 And COX-2 Was Found. In Most Of Cases The Increase In COX-2 Expression Is Associated With Increase In TGF-?1expression, Which May Reveal That TGF-?1 Induce The Expression Of COX-2.Conclusion: COX-2 And TGF-?1 Expression Was Highly Expressed In Solid Variant Of ACC Than In Other Variants. There Was A Significantdirect Correlation Between TGF-?1 And COX- 2; P Value = 0.001 (P-values Less Than 0.05 Were Considered As Statistically Significant)an Increase In COX-2 Expression Is Associated With Increase In TGF-?1expression In All Studied Cases.

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ROLE OF TISSUE ENGINEERING IN WOUND HEALING IN IRRADIATED TISSUES: A REVIEW ARTICLE

Ahmed Alaa El-Din Fouad, Marwa M Hegab, Salwa Farid Ahmed, Soheir Saad Korraa* And Azza Ezz Al-Arab,

ABSTRACT
Radiation Has Deleterious Effects On Different Organs And Tissues. Among The Most Serious Complications In The Dental Fiel, Is The Impaired Wound Healing And The Risk Of Osteoradionecrosis Which Can Complicate Dental Procedures. Tissue Engineering Represents A Promising Model For Enhancing Wound Healing In Irradiated Tissues, Through The Use Of Stem Cells, Scaffolds, And Signaling Molecules To Regenerate The Structure And Function Of Lost Tissues.

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EVALUATION OF SOME PROPERTIES OF GLASS IONOMER CEMENT INCORPORATING HYDROXYAPATITE NANOPARTICLES; AN IN VITRO STUDY

Khaled Mahmoud Fawzy, Mohamed Moustafa Abdel-Moaty, Nermin AlSayed Mahmoud And Asmaa Abdel-Hakeem Metwally,

ABSTRACT


Aim: The Objective Of This In Vitro Study Was To Evaluate The Effect Of Incorporation Of Nano-hydroxyapatite Particles With Three Different Proportions (1 %, 5% And 10%) In To Glass Ionomer Cement (GIC) On Shear Bond Strength To Dentin, Water Sorption And Water Solubility.

Materials & Methods: Experimental Material Powder Was Prepared By Mixing Different Wt% (1%, 5% And 10%) Of Nano-hydroxyapatite (HA) Powder With GIC Powder (GC Gold Label 9 Posterior Restorative) And Evenly Mixed By A Spatula On A Glass Slab. A Total Of Eighty Specimen From GICs [GIC Control (Group I), GIC+1%NH (Group II), GIC+5%NH (Group III) And GIC+10%NH (Group IV)] Were Prepared According The Manufacturer Instructions [Powder / Liquid Ratio (3.6g/1.0g)], Divided As Forty Specimen For Each Test. For Shear Bond Strength Test; Forty Human Posterior Teeth Were Used In This Study. Ten Disks Of 5mm Diameter And 2mm Thickness From Each Tested Material (n=10) Were Prepared And Bonded To Occlusal Dentin Surface Beyond The Dentino-enamel Junction. The Specimens Were Removed From The Molds After 30 Min, And Then Stored At 37?C For 24 Hour. Universal Testing Machine Was Used To Measure The Shear Bond Strength Between The Tested Material And Dentinal Surface. Another Ten Disks Of 10mm In Diameter And 2mm Thickness From Each Tested Material (n=10) Were Prepared For Water Sorption And Solubility Tests. After Complete Setting Of The Specimens, The Original Mass Of Each One (M1) Was Recorded By Using The Digital Balance With An Accuracy Of 0.1 Mg, Then Transferred To Separate Test Tubes Contained Distilled Water And Stored In An Incubator At 37?C For One Week After That, Wet Mass (M2) Then Each Disk Was Placed In A Silica Particles-containing Desiccator And Weighed Daily Within 7 Days To A Constant Finalmass (M3) To Allow Determination Of The Mass Loss. Data Were Collected, Tabulated And Statistically Analyzed By Using One-way ANOVA Followed By Tukey Post Hoc Test.

Results: There Was A Statistically Significantdifference Between Groups Where (p<0.001). The Shear Bond Strength And Water Solubility Of GIC With 10% Nano-hydroxyapatite GIC+10%NH (G4) Had The Highest Values (3.249?0.152MPa) And (252.46 ?9.06 Ug/mm3) Respectively. GIC With 5% Nano-hydroxy-apatite GIC+5%NH (G3) Had The Highst Value In Water Sorption (301.58?12.33 Ug/mm3).

Conclusions: Incorporation Of Nano-hydroxyapatite Particles Within Glass Ionomer Cement Enhanced The Shear Bond Strength Between The GIC And Dentin, Also Increased The Water Sorption And Solubility Of GIC Which Affect Its Physical Properties.

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THE PREVALENCE OF EXTRA ROOT CANALS AND THE ROOT CANAL CONFIGURATION IN MANDIBULAR ANTERIOR IN A SAMPLE OF EGYPTIAN POPULATION USING CONE BEAM COMPUTED TOMOGRAPHY. A HOSPITAL -BASED CROSS SECTIONAL STUDY

Passant Yusuf, Salma Belal Eiid And Ahmed Mohamed Abd El Samad,

ABSTRACT


Aim: The Aim Of This Study Was To Evaluate The Number And Morphological Characteristics Of The Roots And Root Canals In Mandibular Anterior Teeth, Using Cone Beam Computed Tomography. Methods And Materials: In This Cross-sectional Study, A Total Of 165 Of Lower Anterior Teeth Including Centrals (55), Laterals (56) And Canines (54) From 28 CBCT Scans Were Examined. Gender Of Patients Was Registered For Each Scan. The Teeth Were Investigated In Terms Of The Number Of Roots And Root Canals, The Canal Configurationaccording To Vertucci Classificationand The Location Of Canal?s Division.

Results: Teeth With Accessory Canals Represented 24.8% (41 Teeth) Of The Whole Sample, Whereas Teeth With Two Roots Were Represented Only In 2.4% (4 Teeth) And Found In Canines Only. Regarding Canal Configuration,Type I Configurationshowed The Highest Prevalence Of 75.2%, Followed By Type III Representing 21.2%. More Than Half Of The Canals Were Divided In The Middle Third With Prevalence 56.1% (23). Concerning Gender, Double Rooted Teeth Were Only 3 Cases (3%) In Females, And One Case (1.6%) In Males. Lastly, Teeth Showed Almost The Same Distribution On Both Sides Of The Jaw (83 Teeth On The Right Side And 82 On The Left Side).

Conclusions: The Root Canal Morphology Of Mandibular Anterior Teeth Has Great Diversity That It Differs Between Different Races And Populations, And Egyptian Practitioners Should Assume That Second Canal Exists Especially In Incisors And Should Pay Extra Attention To Provide The Best Results.

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ONE-YEAR CLINICAL ASSESSMENT OF INDIRECT RESTORATIONS FABRICATED FROM NANO HYBRID COMPOSITE BLOCKS VERSUS CERAMIC BLOCKS IN BADLY BROKEN TEETH ?A RANDOMIZED CLINICAL TRIAL?

Hamsa Ashraf Abdel Menam, Ahmed EL Zohairy , Adel El Tannir And Shereen Hafez Ibrahim,

ABSTRACT


Aim: To Compare One-year Clinical Performance Of Indirect Restoration Fabricated From Nano Hybrid Composite CAD CAM Blocks And Ceramic Blocks In Restoration Of Badly Broken Vital TeethMethods And Materials: In Two Parallel Groups (n= 42 Restorations), 39 Participants Having Badly Broken Vital Teeth Minimum Of Two Remaining Wall Were Randomly Enrolled In This Trial And Received Either Resin Composite Blocks (Grandio, VOCO, Germany) Or Ceramic Blocks (E.max). Fabricated Restorations Were Cemented According To The Manufacturers? Instructions With The Corresponding Adhesive System. The Restorations Were Assessed Using ModifiedUSPHS Criteria By Two Independent Blinded Assessors At Baseline And 1-year Follow Up Visits. Data Was Obtained And Analyzed Using Independent Student-t Test, Chi-square And McNemar Test For Inter And Intragroup Comparisons. The Significance Level Was Set At ? 0.05.

Results: All The 39 Participants Completed The Trial. There Was No Statistically Significantdifference Between Both Tested Materials For All USPHS Criteria Except For Cavo-surface Marginal Discoloration Favoring Grandio Blocks.

Conclusions: Both Materials Showed An Acceptable Successful Clinical Performance Along 1-year Follow-up Period.

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EFFECT OF H1 RECEPTOR ANTAGONIST ON ALVEOLAR BONE HEALING FOLLOWING TOOTH EXTRACTION IN ALBINO RATS

Nourhan Alaa El-Deen M. Sedky, Bassant Adel Ezzat, Marwa MS Abbassand Heba M Hakam,

ABSTRACT


Aim: The Present Study Was Carried Out To Evaluate The Effect Of H1 Receptor Antagonist H1RA On Alveolar Bone Healing Following Tooth ExtractionMethods: Eight Adult Male Albino Rats With An Average Weight Of 150 To 200 G Had Their Lower Right Firstmolar Extracted And Were Randomly Distributed Into Two Groups, Four Rats As A Control Group Administrated 1 Ml Of Distilled Water And Four Rats As A Promethazine Group Administrated Promethazine Hydrochloride (4.8 Mg/kg).The Rats Were Sacrificedafter 7 Days. Alveolar Bone Healing Following Tooth Extraction Was Assessed By Histological And Histomorphometric Analysis.

Results: Alveolar Bone Healing After 7 Days Following Tooth Extraction Showed Retarded Healing And Lesser Bone Formation In H1 Receptor Antagonist Group As Compared To The Control GroupConclusion: H1 Receptor Antagonist Seemed To Negatively Affect The Early Stages Of Alveolar Bone Healing Following Tooth Extraction.

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