Walid Ahmed Ghanem, Ibrahim Hussein Ahmed, Mohammed Ahmed El- Sholkamy And Islam Mohammed Ibrahim El- Matary,
ABSTRACT
The Purpose Of This Study Was To Evaluate Two Different Methods Used For Promotion Of Extraction Bony Socket Healing (clinically And Histologically).
Materials and Methods: This Study Was Carried Out On Twenty Seven Mature Healthy Dogs With Average Weight 20 Kg. The Animals Were Subjected To Surgical Extraction Of The Lower Second Premolar Atrumatically. The Dogs Were Equally Divided Into Three Groups. Group I; Acted As Control Group. For Group II; The Extraction Sockets Were Filled With Platelet-rich Fibrin (PRF) Alone While Group III; The Extraction Sockets Were Filled With PRF-mixed ?-TCP. All Extraction Sockets Were Closed By Resorbable Interrupted Sutures (3 ? 0 Vicryl). The Extraction Sockets Ridge Dimensions Were Measured By Divider And Ruler. Clinical, Histological Evaluation And Histomorphometric Analysis Were Done After Sacrifying The Animals At 3, 6 & 12 Weeks Post-operatively. The Gathered Data Were Analyzed By Using Kruskal-Wallis Test With The Use Of SPSS Version 14.
Results: Upon Comparing The Three Groups Under Investigation, 3, 6, 12 Weeks After Surgery; The Clinical Healing Of The Three Groups Was The Same Without Complications. 12 Weeks Post-operatively, The Ridge Dimensions Of The Extraction Sockets For Group I (control Group) Showed Pronounced Resorption, Group II (PRF Group) Showed Almost Good Healing With Little Bone Resorption, While Group III (PRF- Mixed ?-TCP Group) Showed Extraction Socket Enlargement, Demonstrating Significant Difference Statistically. Histological Examination Showed Formation Of Woven Bone Within The Extraction Sockets. The Percentage Of Newly Formed Bone Within The Extraction Sockets Measured By Histometry, Showed Statistically Significant Difference, Twelve Weeks Post-operative; The Mean Extent Of Bone Formation In Group I(control Group) 0.281 � 0.105,while Group II (PRF Group) 0.511 � 0.113 And Group III (PRF-mixed ?-TCP Group) The Extent Was 0.661 � 0.088 In A 20 �m2 Surface Area.
Conclusion: The Use Of PRF Is A Successful Procedure For Extraction Socket Healing And Alveolar Ridge Preservation. However, PRF- Mixed ?-TCP Graft Material Showed Synergestic Effect On Bone Healing That Can Be Used For Reconstruction Of Large Bone Defect And Extraction Socket With Destructed Walls.
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