ALVEOLAR RIDGE AUGMENTATION USING BIODEGRADABLE RIGID SYNTHETIC MEMBRANE �A PRELIMINARY STUDY�

Salah El-Din M. Harraz , Nader N. Elbokle And Mohammed M. Khashaba,

ABSTRACT


Purpose: This Preliminary Study Was To Evaluate Clinically And Radiographically The Volume Changes Of Alveolar Bone Grafting Guided By Resorb-x Membrane. Patients And Methods: A Total Of Six Patients With Maxillary Anterior Localized Alveolar Ridge Defects ? 3 Mm Were Selected. The Alveolar Ridges Were Reconstructed With Xenogeneic Bone Graft Particles Guided By Resorb-x Membrane. Linear Measurements And Volume Analysis Of The Changes In Alveolar Ridge Were Obtained Pre-operatively And Four Months Post-operative Using Cone Beam Computed Tomography (CBCT).

Results: Four Months Postoperatively, All Treated Defect Sites Exhibited Satisfactory Bone Formation. Clinical Results Showed Absence Of Any Foreign-body Reactions To Biodegradation Of Resorb-x Membrane And SonicPin Rx�. Measurements Made On CBCT, Four Months Postoperative Showed Statistically Significant Increase In Bone Width With Mean � SD: 2.37 � 1.77 Mm At 2 Mm, 2.46 � 1.56 Mm At 4 Mm, 2.36 � 1.05 Mm And 1.63 � 0.83 Mm At 8 Mm From Crest Of Alveolar Ridge Respectively. There Was Statistically Significant Increase In Bone Volume By 36.15% In The Area Of Newly Formed Bone. No Statistical Significant Changes Was Found In The Density Of Newly Formed Bone When Compared To The Density Of The Native Bone Four Months Post-operatively. Conclusion: The Resorb-x Membrane Is An Improvement In The Search For A Mechanically Strong And Stiff As Well As A Biodegradable System. With Such Modifications In Properties, This Gives Resorb-x Membrane More Promising Chances To Be Used In Guided Bone Regeneration.

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BONE QUALITY AND DENTAL IMPLANT OUTCOMES

Sylvia M.S. Iskandar, Iman A. Radi , Nouran Abdel-Naby And Assmaa Gad Allah,

ABSTRACT
Dental Implants Offered Variety Of Solutions For Retention And Stability Problems Associated With Partial And Complete Dentures. Bone Quality And Quantity Are Critical Factors For Both Implant Placement Decision Making And Its Prognostic Consequences. Low Bone Density (osteoporosis) Affects More Than 200 Million Women Worldwide Aging Between 60 And 90 Years Old. Critical Summary For A Recent Systematic Review Which Was Conducted To Evaluate Implant Failure Related To Low Bone Density (osteoporosis), Which Proved The Review To Be Of No Clear Evidence , However, Due To Inherent Limitations Of The Previous Systematic Review And Availability Of New Studies As Well As Comparing Between Different Techniques, Conducting The Current Systematic Review Was Mandatory. There Are Two Objectives For This Systematic Review: First To Explore The Success Of Implants In Low Bone Density Patients If Compared To Normal Bone Density Ones. Second To Compare Conventional And Special Techniques Used In Literature To Manage Implant Patients With Low Bone Density To Enhance The Success Of The Dental Implant.

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EFFECT OF FINISH LINE STEEPNESS AND CONSTRUCTION TECHNIQUE ON VERTICAL MARGINAL GAP DISTANCE OF MACHINABLE AND PRESSABLE IPS E-MAX CERAMIC COPINGS (AN IN-VITRO STUDY)

Esraa Hashem, Ghada I. Shehab And Hanaa I. Sallam,

ABSTRACT
Purpose. The Purpose Of This Study Was To Assess The Vertical Marginal Gap Distance Of The IPS E.max Ceramic Copings As Affected By Finish Line Steepness And Construction Technique. Material And Methods. Fifty Four IPS E.max Ceramic Copings Were Fabricated With 2 Different Construction Techniques On Two Nickel Chromium Dies With 2 Different Finish Line Steepnesses (1 And 3 Mm). Copings Were Divided According To Their Construction Technique Into Two Main Groups: Group I : Machinable All Ceramic Copings And Group II : Heat Pressed All Ceramic Copings. Each Group Was Further Subdivided Into Two Subgroups According To Different Finish Line Steepness: Subgroup 1: 1-mm Finish Line Steepness And Subgroup 2 : 3-mm Finish Line Steepness. The Vertical Marginal Gap Distance Was Measured Using A Stereomicroscope, And Data Were Statistically Analyzed Using 2-way ANOVA Followed By Pair- Wise Tukey�s Post-hoc Tests. Results. IPS E.max Ceramic Copings Constructed By CAD/CAM Technology With 3 Mm Finish Line Steepness Recorded The Highest Statistically Significant Vertical Marginal Gap Distance Mean Value (111.01 � 8.05�m), While Copings Constructed By Heat Pressed Technique With 1 Mm Finish Line Steepness Recorded The Lowest Statistically Significant Vertical Marginal Gap Distance Mean Value (26.06 � 3.9 �m) Among The Tested Groups . Pair-wise Tukey�s Post-hoc Test Showed That There Was No Statistically Significant Difference Between Copings Constructed By Heat Pressed Technique With 1 Mm And 3 Mm Finish Line Steepness (P=0.329). Conclusion. Increasing The Finish Line Steepness Significantly Increases The Vertical Marginal Gap Distance Especially With CAD/CAM Construction Technique. The Construction Technique Significantly Affected The Vertical Marginal Gap Distance Of IPS Emax Ceramic Copings, With The Superiority Of The Heat Pressing Technique. Clinical Implications. IPS E.max Press Is More Reliable Than IPS E.max CAD For Preparations And Restorations Of Teeth With Increased Degree Of Finish Line Steepness.

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EVALUATION OF THE MARGINAL ACCURACY AND INTERNAL FIT OF METAL COPINGS FABRICATED BY CAD/CAM TECHNIQUES COMPARED TO CONVENTIONAL LOST WAX TECHNIQUE. (AN IN VITRO STUDY)

Amr Ali , Adel El Tannir And Maha Ahmed Taymour,

ABSTRACT
Systems Imply None Or Minimal Influence Of The Dental Laboratory Technician. However, It Is Not Clear Wether Metal Ceramic Restorations Produced By CAD/CAM Systems Show Comparable Adaptation To Those Produced By The Dental Laboratory Technician.

Purpose: This Study Evaluated And Compared The Marginal Gap And Internal Adaptation Of Metal Copings Produced By Four Techniques: Conventional Waxing Technique (CW), Milled Metal Technique (MM), Milled Wax Technique Followed By Conventional Casting (MW1), Milled Wax Technique With Margination Followed By Conventional Casting (MW2)

Materials and Methods: A Master Metal Die Of A Maxillary First Molar Prepared With Chamfer Finish Line Was Produced, Forty Stone Dies Were Poured From Impressions Of The Master Die And Were Randomly Assigned To Each Of The Study Groups (n=10), Metal Copings Were Then Fabricated According To The Study Groups (CW, MM, MW1, MW2). The Metal Copings Were Seated On The Master Metal Die And Held In Place By A Spring Holding Device And The Vertical Marginal Gap Was Measured By A Stereomicroscope Under 10x Magnification At 40 Predetermined Points For Each Specimen. The Internal Gap Was Measured Using The Replica Technique At 7 Predetermined Points For Each Specimen. One Way ANOVA Was Used To Compare Between The Four Groups Followed By Tukey Post Hock Test.

Results: The Least Marginal Gap Was Recorded By The MW2 (47.5 � 3.7�m) With Significant Difference (P<0.05) To The CW (55 � 5.4�m) And MM (60.5 � 7�m Groups) While There Was No Significant Difference With MW1 (50.3 � 5�m). The Internal Gap Results Showed No Significant Difference (P>0.05) Between The Studied Groups With The Least Gap Recorded By MM Group (127 � 42�m). All Results Were Within The Clinically Acceptable Range. Conclusion: CAD/CAM Can Be Used In The Production Of Metal Copings As An Efficient, Time Saving And Aseptic Alternative To Conventional Casting As It Produces Copings With Clinically Acceptable Marginal And Internal Adaptation Values.

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EVALUATION OF OSSEOUS REGENERATION USING BOVINE BONE XENOGRAFT IN EXPERIMENTAL MAXILLARY SINUS FLOOR AUGMENTATION (A HISTOLOGICAL COMPARATIVE STUDY IN RABBITS)

Ghada Gamal Adayil, Manal Mohamed Hosny, Dalia Yehia Ibrahim Ahmed Zaki And Mai Zakaria Ibrahium Mohammed,

ABSTRACT

Objectives: To Study The Effects Of Maxillary Sinus Floor Elevation Using Bovine Bone Xenograft Scaffold In Rabbits.

Materials and Methods: Twelve Male Rabbits That Had Undergone Sinus Lift Procedures Were Divided Into Two Groups, According To The Time Of Euthanasia: Group 1: After One Month And Group 2: After Two Month.

Results: The Augmented Maxillary Sinus Height Was Maintained For Both Groups Over The Entire Experimental Period, While New Bone Area Increased Over Time.

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EFFICACY OF PREOPERATIVE ACECLOFENAC ON POST-ENDODONTIC PAIN: A RANDOMIZED CLINICAL TRIAL

Nermeen Awadallah Abbas Ibrahim, Suzan Abdul Wanees Aminand Shaimaa Ismail Gawdat,

ABSTRACT


Aim: The Aim Of This Prospective, Randomized, Double-blind, Clinical Trial Was To Evaluate The Effect Of A Preoperative, Single, Oral Dose Of Aceclofenac (100 Mg) On Postoperative Pain At 6, 24 And 48 Hours After Single-visit Root Canal Treatment. Methods: Seventy, Endodontic Emergency Patients With Symptomatic Irreversible Pulpitis (SIP) In Posterior Teeth, Randomly Received Either 100 Mg Aceclofenac (Group A, N=35) Or Placebo (Group B, N=35) Tablets 60 Minutes Before The Initiation Of Single-visit Endodontic Therapy. Postoperative Pain Intensity And Incidence At The Different Pain Categories (No, Mild, Moderate, Severe) Was Assessed 6, 24, And 48 Hours Postoperatively Using Heft-Parker Visual Analogue Scale (HP-VAS). Data Were Statistically Analyzed And The Significance Level (?) Was Set At 0.05.

Results: There Was No Significant Difference Between The Two Groups Regarding The Main Baseline Characteristics Including: Age, Gender, Pre-operative Pain And Canal-number Distribution (p>0.05). Results Showed No Significant Difference Between Both Groups Regarding Postoperative Pain Intensity Or Incidence 6, 24 And 48 Hours Postoperatively (p >0.05). Pain Intensity Significantly Decreased Over Time (p<0.05) Conclusion: Preoperative Administration Of A Single, Oral Dose Of 100 Mg Aceclofenac Did Not Seem To Affect The Postoperative Pain Within The First 48 Hours After Single-visit Root Canal Treatment.

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EVALUATION OF SHAPING ABILITY OF DIFFERENT NITI SYSTEMS �USING CONE BEAM COMPUTED TOMOGRAPHY� IN A VITRO STUDY

Mona E. Shabana, Salma H. Al-Ashry And Ahmed M. Ghobashy,

ABSTRACT
Objective: The Aim Of The Current Study Was To Compare Between Rotation Motion (ProTaper Universal And ProTaper Gold) And Reciprocation Motion (WaveOne And WaveOne Gold) In Shaping Ability Of Curved Root Canal By Assessment Of Canal Transportation, Centering Ability And Remaining Dentin Thickness And Changes In Canal Curvature Using CBCT Methods: Forty Extracted Human Mandibular First Molars With Mesiobuccal Canal Curvature Ranged 20-35 Degrees Were Used In The Study. Decoronation Of The Teeth At 15 Mm Length Each Tooth Was Radiographed From The Buccal View With #15 K-file Inside The Mesio-buccal Canal Adjusted To The Apical Foramen Using Vista Scan Digital X-ray Machine And Schneider Angle Was Measured. Teeth Will Be Classified Into Two Main Groups Group I With 20 Teeth For Rotation Motion And Group II For Reciprocation Motion. Each Group Will Be Further Subdivided Into Two Subgroups According To The Type Of File System .Sub Group A For Universal System And Group B For New System. Group I: Ten Teeth Were Shaped Using PU For Subgroup A And Another Ten Teeth Were Shaped Using PTG For Subgroup B According To The Manufacture Instructions And Ending Up To File F2. Group II Subgroup A And Subgroup B Ten Teeth Were Shaped Using Primary WO 25/.07 With X Smart Plus Motor In Subgroup A, Another Ten Teeth Were Shaped Using Primary WOG 25/.08 With X Smart Plus Motor With Wave One Gold Setting In Subgroup B. Both Systems Were Used According To Manufacturer Instruction. Using Cone Beam Computed Tomography With Fused Image, Subtracting The Un-instrumented Dentin From The Instrumented Canal Using On Demand3D Software, Axial Cuts Were Carried Out At 3mm, 5mm And 7mm In The Root. Assessment Of Degree And Direction Of Transportation, Centring Ability And Change In Canal Curvature Was Done Using CBCT. Data Were Collected, Tabulated And Statistically Analyzed In Tables And Figures. Friedman�s Test Was Used To Compare Between The Different Levels Within Each System. Dunn�s Test Was Used For Pair-wise Comparisons When Friedman�s Test Is Significant.

Results: In BL Direction, At 5 Mm Root Level, ProTaper Gold Showed The Statistically Significantly Highest Mean Centering Ratio, While ProTaper Universal Showed The Statistically Significantly Lowest Mean Centering Ratio. There Was No Statistically Significant Difference Between The Four Systems Regarding Change In Canal Curvature Conclusion: The Two Motions Were Comparable As Regards To The Amount Of Dentin Removal, Except At 7 Mm, Reciprocation Revealed Lower Mean Value.As Regards Transportation Direction, The Four Systems Had A Tendency Toward Transportation To The Mesial Direction.Reciprocation Motion Exhibited Superior Performance Compared With The Rotation Motion In Transportation At 7 Mm The Four Different File Systems Straightened Root Canal Curvature Similarly.

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MIDKINE AND KI-67 EXPRESSION IN SALIVARY GLAND TUMORS (AN IMMUNOHISTOCHEMICAL STUDY)

Amr Helmy El Bolok, Enas Alaa El Din Abd El Aziz, Mai Ibrahim Sholqamy And Sara Moustafa Mahmoud,

ABSTRACT
Aim Of Study: To Investigate The Expression Of Ki-67 And Midkine In Salivary Gland Tumors And Evaluate The Correlation Between MK And Ki-67 Expression In SGTs.

Materials and Methods: Twenty Five Formalin Fixed Paraffin Blocks Of SGTs Were Stained Immunohistochemically For Ki-67 And MK. Immunostainig Was Measured As Area Fraction And Results Were Analyzed Statistically. Value <0.05 Was Considered Significant.

Results: All Cases Of SGT Showed Positive Reaction To Ki-67 And MK. A Significant Positive Correlation Was Found Between Ki-67 And MK Expression In SGTs. Conclusion: MK And Ki-67 Expression Are Higher In Malignant Than Benign Salivary Gland Tumors, So Evaluation Can Provide Information About Aggressiveness Of The Tumor.

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FRACTURE RESISTANCE OF MAXILLARY POSTERIOR FIXED PARTIAL DENTURE CONSTRUCTED ON MUTILATED ABUTMENTS. A FINITE ELEMENT STUDY

Ahmad K. Mubarak, Manal R. Hassan And Mohammed M. Shalaby,

ABSTRACT
Aim Of The Study: The Aim Of This Study Was To Investigate Fracture Resistance Of Maxillary Posterior Fixed Partial Denture Constructed On Mutilated Abutments Using Finite Element Analysis.

Materials and Methods: Twenty Four 3 Units �3-Y-PS Zirconia� Fixed-fixed Partial Dentures Were Constructed On 48 Uniformly Prepared Abutments (24 Maxillary Second Premolars+24 Maxillary Second Molars). The Zirconia Fixed-fixed Partial Dentures Were Divided According To The Vitality Of The Adjoing Abutments Into Two Main Groups. Group (A): The Adjoining Abutments Were Non Endodontically Treated That Restored With Composite Cores. Group (B): The Adjoining Abutments Were Endodontically Treated Restored With Glass Fiber Posts Cemented With Rely X Cement And Composite Cores Build Up. Each Group Of (A) And (B)were Subdivided Into: Control Group (sound Abutments With No Missed Wall) And Experimental Group. The Experimental Group Consisted Of 3 Subgroups; One Wall Missed (A1 Or B1), Two Walls Missed (A2 Or B2) And Three Walls Missed (A3 Or B3). A Vertical Compressive Load With 3mm Diameter Indenter Was Applied To The Central Fossa Of The Pontic Using Universal Testing Machine. A 5Kg Load Was Applied At A Crosshead Speed Of 1mm/min Until Fracture Occurred. A Finite Element Models Were Conducted To Study Stress Distribution On The Component Of The Fixed-fixed Bridges Of All Studied Groups And Subgroups , Besides, Comparing Between Zirconia And Lithium Disilicate Ceramics(E Max) As Different Bridge Construction Materials.

Results: The Highest Fracture Resistance Mean Value Was Recorded For The Control Group Of The A Abutments (Ac)(3095.22 �284.94N). The Fracture Resistance Means Of The Subgroups Were Recorded As A1(2978.52N)>Bc(2897.1N)>A2(2687.13N)>B1(2341.29N)>B2(2118.76)>A3(1943.32N)>B3(1921.79N). While The Lowest Fracture Resistance Mean Value Was Recorded For B3subgroup (1921.79 �75.26N) Which Is The Non Endodontically Treatd Abutments With 3 Missing Walls (the Most Mutilated Subgroup). Conclusion: The Fracture Resistance Of The Fixed-fixed Partial Denture Was Directly Proportional To The Adjoining Abutments Existing Walls Number. The Zirconia Material Enhanced The Fracture Resistance Of The Fixed Prosthodontics Due Toitshigher Ability For Stress Distribution Than The Lithium Di-silicate Ceramics(E-Max).

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DIAGNOSTIC EFFICACY OF ANNEXIN A1 IN INDUCED DYSPLASIA AND SQUAMOUS CELL CARCINOMA OF TONGUE IN EXPERIMENTAL RATS

Doha Mohammed Afifi, Amal Hassan Abdel-Rahman And Heba Mahmoud Dahmoush,

ABSTRACT
Background: Oral Squamous Cell Carcinoma Is A Malignant Tumor With Poor Prognosis And Therefore The Discovery Of Markers For Early Signs Of Malignant Transformation Would Be Of Critical Importance In Clinical Diagnosis. In This Study We Aimed To Detect The Changes In ANXA1 Immunoexpression In Tissues Of Normal Rat Tongue Mucosa And In Induced Dysplasia And OSCC.

Materials and Methods: 25 Rats Were Used, Divided Into 2 Groups: A Control Group (5 Rats With No Induction) And Experimental Group (20 Rats Which Received Topical Painting Of DMBA And Formaldehyde For Induction Of Dysplasia And SCC). Tongue Dissection Was Performed At Euthanization Dates. Area Percent Of Immunohistochemical Expression Of ANXA1 Was Measured By Software Leica Qwin 500.

Results: ANXA1 Was Expressed In The Cell Membrane Of Normal Tongue Mucosa And Loss Of This Expression Was Frequent In Both Dysplasia And OSCC. A Statistically Significant Difference In ANXA1 Expression Was Present Between Normal Tongue Mucosa And Dysplastic Lesions Or OSCC. Conclusion: ANXA1 Immunostaining Has A Potential Utility For The Detection Of Epithelial Dysplasia.

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