Mennatalla A. Mehena, Mohammed N. Anwar And Farid S. El-Askary,

ABSTRACT


Purpose: The Purpose Of This Study Was To Evaluate The Effect Of Bonding Protocols And Resin Cement Type On Push-out Bond Strength Of Fiber Reinforced Composite Post To Radicular Dentin.

Materials and Methods: A Total Of 72 Human Lower Premolar Teeth Were Randomly Assigned To 6 Groups (n=12) According To The Two Experimental Factors Being Investigated (bonding Protocol And Type Of Resin Cement). After Decoronation And Pulps Extirpation, The Post Spaces Were Prepared. Adhesive Was Applied On Radicular Dentin And Cured Following The Bonding Protocols Investigated (according To Manufacturer Recommendation Curing Time, Doubling The Manufacturer Recommendation Curing Time And Co-curing). Resin Cement Was Injected Inside The Root Canal And The Post Was Inserted And Either Light Cured For 40s (dual-cure Resin Cement) Or Left To Cure Chemically (chemical-cured Resin Cement). After 24 Hours, Each Root Was Sliced Into Three Slices. Each Slice Was Subjected To Push-out Bond Strength Test At A Crosshead Speed 0.5 Mm/min. ANOVA And Student T-test Were Used To Analyze The Data.

Results: Two-Way ANOVA Revealed That Neither The Bonding Protocol Nor The Type Of Cement Had Significant Effect On Push-out Bond Strength (P=0.408 And P=0.089 Respectively); While Their Interaction Showed Significant Effect On Push-out Bond Strength (P<0.0001). Conclusion: The Effect Of Curing Protocol Is Dependent On The Type Of Cement. In All Bonding Protocols, The Type Of Cement Has An Influence On The Bonding Of Fiber Post To Root Canal Dentin.

Reema A. Al-Eryani, Ghada A. El-Baz, Wael M. Abd-Alkhalek, Essam M. Abd-Allahand Mohamed Sherif M. Salah El-Din,

ABSTRACT
Aim Of The Study: To Study The Variations In Some Salivary Parameters (pH, Ca2+, SIgA, And Lysozyme) And Their Influence On Dental Caries Status In Egyptian And Yemenis Asthmatic Children. Subjects And Methods: This Study Was Carried Out On Two Hundred Children Of Both Sexes With Age Ranged From 6-10 Years. The Cases Were Divided Into Two Main Groups; One Hundred Children From Egypt And One Hundred Children From Yemen. Each Group Was Subdivided Into Two Subgroups; Fifty Children Asthmatic And Fifty Children Healthy. Dental Caries Was Assessed For Each Child According To WHO Criteria (1997) For Detection Of Caries Using DMFS For Permanent Dentition. Saliva Samples Were Collected From Each Child To Measure: PH, Ca2+, SIgA, And Lysozyme. The Correlation Between Different Salivary Parameters And Dental Caries In Permanent Dentition Was Evaluated.

Results: Asthmatic Children Showed No Significant Differences In All Studied Variables Between Egyptian And Yemeni Children. While For Healthy Children, Egyptians Showed Statistically Significant Higher Mean PH Level And Lower Mean Ca2+ And Lysozyme Levels Than Yemeni Children. In Comparing Between Asthmatic And Healthy Children, Egyptian Asthmatic Children Showed Statistically Significant Lower Mean PH Level And Higher Mean Ca2+, SIgA, And Lysozyme Levels Than Healthy Children. Regarding Yemeni Asthmatic Children, There Were Statistical Significant Higher Mean PH And Lysozyme Levels And Lower DMFS Score Than Healthy Children. Egyptian Healthy Children Showed A Statistically Significant Positive Correlation Between DMFS Score And SIgA Levels. Regarding Yemeni Asthmatic Group, There Was A Statistically Significant Positive Correlation Between DMFS Score And SIgA And Negative Correlation Between DMFS Score And Ca2+ Level. While The Yemeni Healthy Children Showed A Positive Correlation Between DMFS Score And SIgA. ROC Curve Analysis Showed That Saliva Samples Of Children With Lysozyme Above 5.80 Ng/ml And 4.66ng/ml For Egyptian And Yemenis Respectively, Can Be Suspected For Asthma With Accuracy Of 66% And 64% In Both Groups Respectively. Conclusion: Salivary Analysis Revealed An Overall Altered Salivary Composition In Children With Asthma, Indicating A Compromised Oral Environment In These Patients And Suggesting Salivary Analysis As An Additional Diagnostic Tool For Allergic Diseases.

Reema A. Al-Eryani, Ghada A. El-Baz, Wael M. Abd-Alkhalek, Essam M. Abd-Allah And Mohamed Sherif M. Salah El-Din,

ABSTRACT
Aim Of The Study: To Study The Variations In Some Salivary Parameters (pH, Ca2+, SIgA, Lysozyme) And Their Influence On Dental Caries Status In Egyptian And Yemenis Asthmatic Children. Subjects And Methods: This Study Was Carried Out On Two Hundred Children Of Both Sexes With Age Ranged From 6-10 Years. The Cases Were Divided Into Two Main Groups; One Hundred Children From Egypt And One Hundred Children From Yemen. Each Group Was Subdivided Into Two Subgroups; Fifty Children Asthmatic And Fifty Children Healthy. Dental Caries Was Assessed For Each Child According To WHO Criteria (1997) For Detection Of Caries Using Defs For Primary Dentition. Saliva Samples Were Collected From Each Child To Measure: PH, Ca2+, SIgA, And Lysozyme. The Correlation Between Different Salivary Parameters And Dental Caries In Primary Dentition Was Evaluated.

Results: Asthmatic Children Showed No Significant Differences In All Studied Variables Between Egyptians And Yemenis. While For Healthy Children, Egyptians Showed Statistically Significant Higher Mean PH Level And Defs Score And Lower Ca2+ And Lysozyme Levels Than Yemeni Children. In Comparing Between Asthmatic And Healthy Children, Egyptian Asthmatic Children Showed Statistically Significant Lower Mean PH Level And Higher Mean Ca2+, SIgA, And Lysozyme Levels Than Healthy Children. Yemeni Asthmatic Children Showed Statistically Significant Higher Mean PH And Lysozyme Levels Than Healthy Children. Concerning Defs, All In Egyptian Or Yemeni Children As Well As The Whole Sample; Asthmatics Showed Lower Mean Defs Scores Than Healthy Children. There Was A Statistically Significant Negative Correlation Between Defs Score And Lysozyme Level In Egyptian Asthmatics. Egyptian Healthy Showed A Negative Correlation Between Defs Score And PH Level And Positive Correlation With Ca2+ Level. Concerning Yemeni Asthmatic Group, There Was A Statistically Significant Positive Correlation Between Defs Score And SIgA And Negative Correlation Between Defs Score And Lysozyme. While For Yemeni Healthy Children, There Was A Statistically Significant Positive Correlation Between Defs Score And PH Level. ROC Curve Analysis Showed That Saliva Samples Of Children With SIgA Above 271.0 �g/ml And 304.0 �g/ml For Egyptian And Yemenis Respectively, Can Be Suspected For Asthma With Accuracy Of 68% And 64% In Both Groups Respectively. Conclusion: Salivary Analysis Revealed An Overall Altered Salivary Composition In Children With Asthma, And Suggesting Salivary Analysis As An Additional Diagnostic Tool For Allergic Diseases.

Arzaq Sami Abdulrazzaq, Mohamed Abdul Magied Katamish And Amr Amin Ghanem,

ABSTRACT
Objective: The Aim Of This Study Was To Evaluate The Effect Of Mesenchymal Stem Cells In Healing Of Segmental Bony Defects.

Materials and Methods: The Study Was Conducted On Sixteen Skeletally Mature New Zealand Rabbits Weighing 2 To 2.5 Kg. An Approximately 5 Mm Segmental Defect Was Created In The Tibia Of The Animals After The Fixation Of The Tibia With Plate And Screws. We Injected MSCs Into The Defects In The Study Group While The Defects Of The Rabbits Of The Control Group Were Left Empty. All Of The Animals Were Sacrificed On Postoperative Day 22. Digital Radiodensitometric Analysis, Histologic And Histomorphometric Examinations Were Performed On The Harvested Tibia. The Data Were Statistically Analyzed.

Results: There Was Highly Significant Difference Between MSCs Group And Control Regarding Bone Density, Trabecular Bone Thickness And Area Percentage Of Osteoid Tissue. Conclusion: MSCs Showed Promising Results In Improving The Healing Of Segmental Bone Defects In Macroscopic And Microscopic Levels.

Lamia Mohamed Khairy, Mahmoud Hamdy, Adel El Bardissy And Mohamed Abo El Yazeed,

ABSTRACT


Purpose: The Purpose Of This Split Mouth Randomized Controlled Study Was To Compare Pain In Formocresol Pulpotomy And Zinc-oxide And Eugenol Pulpectomy In The Treatment Of Vital Pulp Exposure In Primary Incisors. Methods: Contralateral Pairs Of Incisors Were Randomly Assigned To Receive Formocresol Pulpotomy Or Zinc-oxide And Eugenol Pulpectomy, The Incisors Were Restored With Preveneered Stainless Steel Crowns And Were Followed Up Clinically For 12 Months.

Results: Pain Was Not Reported In Relation To Any Incisor In Both Groups. There Was No Statistical Significant Difference In Pain Between Pulpotomy And Pulpectomy Groups At Different Follow Up Periods. Conclusion: Both Pulpotomy And Pulpectomy Techniques Can Be Used Successfully In The Treatment Of Carious Vital Pulp Exposure In Primary Incisors. Taking Into Account The Success Rates, Reduced Time And Cost Of Pulpotomy, Choosing Of Pulpotomy Instead Of Pulpectomy Could Be Preferred.

Nehall Alaa El Din Abd El Lattif, Adel Abd El Azim El Bardissy And Hany Mohamed Saber,

ABSTRACT


Aim: To Evaluate The Success Rate Of Hall Technique And Indirect Pulp Capping For Managing Primary Molars With Deep Carious Lesions In A Group Of Egyptian Children. Subjects & Methods: A Total Sample Size Of 74 Mandibular Primary Molars. Patients Were Randomly Divided Into 2 Equal Groups, Group A (Hall Technique) And Group B (Indirect Pulp Capping). Indirect Pulp Capping In The Current Study Was Performed Then Teeth Were Finally Covered By Preformed Metal Crowns. Clinical And Radiographic Assessments Were Performed At 3, 6 And 9 Months Postoperatively. Hall Technique Was Performed, And Clinical And Radiographic Assessments Were Performed At 3, 6 And 9 Months Postoperatively.

Results: The Results Of The Study Showed Insignificant Difference Between Both Groups Regarding Postoperative Pain. On Comparing The Overall Clinical Success Of The Two Groups At 3, 6 And 9 Months Group B (IPC) Showed Higher Clinical Success Than Group A (HT). However, There Was No Statistically Significant Difference Between The Two Groups. While, When Comparing The Overall Radiographic Success Between Group A And Group B At 3, 6 And 9 Months; Both Showed 100% Radiographic Success With No Difference Between The Two Groups.

Conclusions: The Hall Technique Appears To Offer An Effective Treatment Option For Carious Primary Molars And It Is A Simplified Method And Considered Easier Than Conventional Restorative Treatment Of Carious Lesions. The Clinical And Radiographic Success Of The Hall Technique Is Comparable To Indirect Pulp Capping.

Mohamed M. Ammar, Gihan H. Waly, Sayed H. Saniour And Taheya A. Moussa,

ABSTRACT
The Aim Of This Study Is To Develop An Injectable Thermo-sensitive Hydrogel Loaded With Freeze-dried Platelet Concentrate And To Characterize This Hydrogel Regarding Its Gel Formation, Biodegradation And Rheological Properties. A Thermo-sensitive Chitosan-based Hydrogel Was Prepared And Its Biodegradation Rate Was Investigated. The Hydrogel Was Loaded With Freeze-dried Platelet Concentrate (FDPC) At Different Concentrations (5 Mg/ml, 10 Mg/ml And 15 Mg/ml) And The Viscosity Of The Unloaded And Loaded Hydrogel Was Investigated As The Temperature Was Raised From 25�C To 37�C. Results Showed That The Hydrogel Lost About 35% Of Its Weight During 32 Days. All FDPC-loaded Hydrogel Groups Showed Lowered Initial Viscosity Of The Hydrogel But FDPC Didn?t Affect The Sol-gel Transition In Any Group In Comparison To The Unloaded Control Group. Accordingly, It May Be Concluded That FDPC Can Be Loaded Within A Thermo-sensitive Hydrogel That Offers The Ease Of Application And Delivery Of Platelet Concentrate Which Can Be Beneficial In Periodontium Regeneration.

Abd El-Ghany L.B., El-Hossary W.H. And Hassan M.M.A,

ABSTRACT
Objective: The Aim Of This Study Was To Evaluate The Expression Of P53 Gene Following Treatment Of Induced Oral Cancer, In Hamster Buccal Pouch (HBP), With 0.001 Mg/kg Body Wt Thymoquinone (TQ) Loaded On Gold Nanoparticles (GNPs).

Materials and Methods: The Study Was Done On Archival Paraffin Blocks To Study The Effect Of Different TQ Preparations On The Chemically-induced Squamous Cell Carcinoma (SCC) In The (HBP). The Chemical Carcinogen 0.5% 7,12 Dimethyl Benz-(a)-anthracene (DMBA), Was Topically Applied To HBP For 14 Weeks. The Paraffin Blocks Represented Buccal Pouches From 55 Male Syrian Golden Hamsters, Weighed 90-120 Grams. They Were Divided Into 4 Major Groups: Group A (control Groups): A1 (20 Animals) Served As Negative Control Group (did Not Receive Any Treatment), And A2 (5 Animals) Served As Positive Control (painted With DMBA For 3 Times/week For 14 Weeks). Group B: (30 Animals) As The Experimental Groups (painted With DMBA 3 Times/week For 14 Weeks) And Then Divided Into Group B1:5 Animals Were Euthanized After 3 Weeks Of I.p Injection Of 0.001 Mg/kg Body Wt TQ, Group B2: 5 Animals Were Euthanized After Six Weeks Of I.p Injection Of TQ, Group B3: 5 Animals Were Euthanized After 3 Weeks Of I.p Injection Of GNPs, Group B4: 5 Animals Were Euthanized After 6 Weeks Of I.p Injection Of GNPs, Group B5: 5 Animals Were Euthanized After 3 Weeks Of I.p Injection Of TQ-GNPs And Group B6: 5 Animals Were Euthanized After 6 Weeks Of I.p Injection Of TQ-GNPs. H&E Stain Was Performed To Confirm The Histopathological Changes And Immunohistochemical Stain For P53.

Results: Positive Control And Experimental Groups (B1-B5) Showed Different Degrees Of Epithelial Dysplasia And Intense P53 Expression(+3) Whereas Group B6 Showed Moderate P53 Immune Reactivity (+2) With Focal Areas Of Variable Dysplastic Grades Along The Epithelial Lining. I.e, The Most Effective Treatment Was Obtained Only Through This Group. Conclusion: TQ (0.001 Mg/Kg Body Wt) Loaded On GNPs, Was Effective In Partial Restoration Of P53 Activity, Especially When Used For 6 Weeks. The Follow Up-timing Of The Present Study Appears Short To Explore The Full Effect Of TQ-GNPs On That Model Of Induced-SCC.

Ahmed Yahia Mohamed, Ahmed G. Ahmed And Emad Mohamed T. Agamy,

ABSTRACT
Objective: The Aim Of This Study Is To Compare The Influence Of Two Different Bar Materials On The Stress Distribution In Two Mandibular Implant Supported Overdentures, One Retained By A Titanium Bar And The Other Retained By A Zirconium Bar Attachment With Standard Bar Dimensions And Cross Section, Using Finite Element Analysis (FEA).

Materials and Methods: A Digital 3D Model Simulating A Mandibular Edentulous Situation Was Constructed, The Surface Of The Model Was Modified To Simulate The Mucosa And An Overdenture Supported By Two Implants Placed In Canine Area And Retained By A Bar Attachment, Two Models Were Created By Duplication, The Only Difference Was The Material From Which Bar Was Fabricated (cobalt Chromium And Zirconium), Two Types Of Loads Were Applied To The Model: Total Of 150 N Vertical And 45 Degree Oblique Loads On The Right First Premolar, Second Premolar And First Molar. The Stress Distribution Around Peri-implant Bone, Implant, Mucosa And Overdentures Was Recorded.

Results: The Maximum Recorded Stresses Under Vertical Loading Were 388.146 Mpa While Under Oblique Loading Were 247.667 Mpa. No Failure Occurred In Any Part Of The Model. All Maximum Stresses Were Less Than The Yield Strength And Within The Biological Range. Conclusion And Clinical Significance: Within The Limitations Of The Current Study, It May Be Conducted That The Use Of Zirconium Bar Exhibited Better Stress Distribution Than Co-Cr Bar.

Shima M. Abdel-Hamed, Magdy M. Ali And Dalia A. Ahmed,

ABSTRACT


Introduction: This Study Evaluated And Compared Sealing Ability And Adaptation Of Mineral Trioxide Aggregate (MTA) And Total Fill Root Repair Material (RRM) When Used In Repair Of Furcation Perforation. Method: 72 Extracted Human, Permanent Mandibular First Molar Were Used In This Study. The Occlusal Surface Of The Crowns Were Reduced To 3 Mm Coronal To The Cemento-enamel Junction, And The Roots Were Amputated 3 Mm Apical To The Furcation Area Using A Diamond Disc . A Conventional Endodontic Access Opening Was Made In Each Sample By Using #12 Tapered Stone With Round End. Flowable Composite Was Used To Seal The Orifices Of Each Canal . Perforation Was Made In The Center Of The Pulpal Floor Using A High Speed # 4 Round Bur. The Samples Were Divided Into 2 Groups According To The Test Used. Group (A), Leakage Study Were Subdivided Into 4 Subgroups: 2 Experimental (TotalFill, MM?MTA) And 2 Control (positive And Negative). Group (B) Marginal Adaptation Study Were Subdivided Into 2 Subgroups(TotalFill, MM?MTA). For Sealing Test, All Samples Were Completely Coated With Two Successive Layers Of Clear Nail Varnish Except For The Perforated Area, The Dye Penetration (Clearing) Method Was Used. Liner Dye Penetration Was Measured Under Stereomicroscope. To Evaluate The, The Interface Between The Repair Materials And Perforation Margins Was Measured Under SEM; Data Was Recorded Using Computer Software.

Results: TotalFill Showed Lower Non Significant Leakage Percentage Than MM-MTA. Also There Was No Statistically Significant Difference Between Marginal Adaptation Of The Two Materials.

Conclusions: Sealing Ability And Marginal Adaptation Of TotalFill Comparable To MM-MTA.