COMPARATIVE EVALUATION OF POSTOPERATIVE PAIN AFTER PULPOTOMY IN CARIOUSLY EXPOSED VITAL IMMATURE FIRST PERMANENT MOLAR USING CALCIUM HYDROXIDE AND CALCIUM SILICATE-BASED MATERIAL (BIODENTINE?): A RANDOMIZED CONTROLLED TRIAL

Shereen H Elshamy, Sherine E Taha , Amr E Abd Elatif And Ahmed M Abd ELsamad,

ABSTRACT
The Aim Of This Study Was To Evaluate Postoperative Pain After Pulpotomy In Cariously Exposed Vital Immature First Permanent Molars Using Calcium Hydroxide And Calcium Silicate-based Material (Biodentine ?).

Materials and Methods: This Study Was Carried Out On Patients Attending Outpatient Clinic In Pediatric Dentistry And Dental Public Health Department - -Faculty Of Dentistry ? Cairo University ? Egypt. A Total Of Thirty Five Patients Had Thirty Eight Vital Immature First Permanent Molar With Deep Caries, Who Satisfied For The Eligibility Criteria And Completed Follow Up Period. Their Age Ranged Between Six Years To Nine Years Old With Mean Age 7.5+/-1 Years. All Teeth Were Mandibular (twenty Mandibular Right 1st Permanent Molars And Eighteen Mandibular Left 1st Permanent Molars). Pulpotomy Was Performed In This Study To Preserve The Vitality And Function Of The Remaining Radicular Pulp Tissue Then Followed By Application Of One Of Investigated Pulp Capping Materials.

Results: When Comparing Postoperative Pain Between The Calcium Hydroxide Group And Biodentine? Group, There Was No Statistically Significant Differences Between Them. Conclusion: After A 12- Months Postoperative Period, Biodentine? Proved Very Effective As A Successful Pulpotomy Agent In Young Permanent Teeth.

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T-SCAN EVALUATION FOR DIFFERENT TYPES OF OCCLUSION IN MANDIBULAR OVERDENTURE RETAINED BY TWO SPLINTED MINI IMPLANTS (IN VIVO STUDY)

Rabab Magdy Sayed, Marwa Ezzat Sabet And Hebatallah Tarek M. Abdallah,

ABSTRACT


Purpose: To Evaluate The Stress Distribution In Mandibular Overdenture Retained By Two Splinted Mini Implants Using Monoplane And Lingualized Occlusion In Setting Of Teeth Using T-Scan.

Materials and Methods: Fourteen Patients Were Selected According To The Inclusion Criteria, The Participants Were Stratified Equally Into Two Groups, Patients Were Assigned To Receive Either Monoplane Or Lingualized Occlusal Schemes To Their Overdentures. For Each Patient Placement Of Two Mini-implants In The Mandible At The Canine Region Was Done, Bar Joint Attachment Was Used To Splint The Mini Implants. Each Implant Was 2.5 Mm In Diameter And 10 Mm In Length. T-scan Occlusal Load Analysis Records Were Done In Centric Occlusion, The Records Was Used To Analyze The Biting Force Of The Denture As A Full Closure Force Movie Recording, Then Time Vs. Force Graph Of That Force Movie Is Accomplished. T-scan Records Were Taken Three Times For Each Patient In The Two Groups, Immediately After Loading, Three Months And Six Months Of Loading.

Results: Within The Limitation Of This Study, The Results Revealed That The Effect Of Time On Load Distribution For Monoplane Ana Lingualized Groups Showed Increase In The Anterior Region Stresses But These Increases Were Statisticaly Insignificant, Also The Effect Of Different Occlusal Schemes On Load Distribution For Follow Up Periods Was Statistically Significant. The Results Also Revealed No Statistically Significant Difference Between Occlusal Forces Within The Same Group At Different Follow Up Period.

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DOES THE MARGINAL THICKNESS OF HYBRID CERAMICS VENEERS AFFECT THE EDGE STRENGTH?

Dorotea Ashraf Fahmy, Maged El Hakim And Tarek Salah Morsi,

ABSTRACT
Aim Of The Study: Thin Veneers Are Subjected To Marginal Chipping During Milling And Clinical Procedures. Thus, This Study Aimed To Evaluate The Edge Strength Of VitaEnamic, EmpressCAD And Cerasmart With Three Veneer Marginal Thicknesses (0.2, 0.3 And 0.5mm). Methodology: Three Natural Teeth Of Similar Dimensions Were Collected And Prepared For Laminate Veneers. Each Prepared With Thicknesses (0.2, 0.3, 0.5mm), Duplicated Into 45 Polymethylmethacrylate (PMMA) Resin Dyes Using Zirkonzahn Machine. Forty-five Veneers (15 Of Each Material) Were Milled Using CEREC System. Each Subdivided Into Three Equal Subgroups (n=5) Of Veneer Thicknesses (0.2, 0.3, 0.5mm). Veneers Were Cemented Using RelyXveneer And Edge Strength Was Tested Using A Diamond Vickers Indenter At A Distance Of 0.5mm Away From The Margin At Crosshead Speed Of 0.5mm/min. Load Was Applied Until Failure Occurred, Followed By Fractographic Analysis.

Results: There Was No Statistically Significant Difference Between The Three Ceramics With 0.2 Or 0.3 Mm Thicknesses. While 0.5 Mm Thickness, Cerasmart Showed Statistically Significantly Highest Mean Edge Strength. Among The Thicknesses, Cerasmart 0.5 Mm Showed Statistically Significantly Highest Mean Edge Strength. Conclusion: Among The Materials, Cerasmart Showed Highest Mean Edge Strength Value. Throughout The Veneer Thicknesses, 0.5mm Showed Highest Mean Edge Strength Value With Cerasmart Only.

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EFFECT OF PREOPERATIVE SINGLE-DOSE CLINDAMYCIN ON POSTOPERATIVE ENDODONTIC PAIN IN PATIENTS WITH SYMPTOMATIC APICAL PERIODONTITIS: A RANDOMIZED CONTROLLED TRIAL

Nermeen S.G. AlSedawy, Suzan A.W. Amin And Shaima?a I. Gawdat .,

ABSTRACT


Aim: The Aim Of This Prospective, Randomized, Placebo-controlled Clinical Trial Was To Evaluate The Effect Of Pre-operative, Single-dose Clindamycin On Post-operative Pain In Patients With Symptomatic Apical Periodontitis Treated In One Visit. Methods: Seventy-two Participants Diagnosed With Symptomatic Apical Periodontitis In Their Mandibular Posterior Teeth Were Included. Patients Were Randomly Assigned Into Either Of Two Groups: Clindamycin Group, Where A Pre-operative, Single-dose Of Clindamycin (600 Mg) Or Placebo Group, Where Pre-operative Placebo Was Given (n=36). After 30 Minutes Of Receiving Medication, Root Canal Treatment Was Performed In A Single Visit. Patients Were Instructed To Rate Their Pain Felt After Endodontic Procedure In A Pain Diary At 6, 12, 24, 48, 72 Hours And At Day 7 Using A Numerical Rating Scale (NRS). Data Were Statistically Analyzed And The Significant Level (�) Was Set As 0.05.

Results: Both Groups Were Similar Regarding Baseline Characteristics, Including: Age, Gender, Canal-number Distribution, Tooth Type And Preoperative Pain (p>0.05). There Was No Statistically Significant Difference Between Both Groups In Post-operative Pain Intensity Or Incidence At Any Of The Follow-up Time Points (p>0.05). Conclusion: Pre-operative Administration Of A Single-dose Of 600 Mg Clindamycin Does Not Seem To Affect Post-operative Pain Intensity Or Incidence For Patients With Mandibular Posterior Teeth With Symptomatic Apical Periodontitis Treated In A Single Visit.

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DEVIATION BETWEEN PLANNED AND ACTUAL IMPLANT POSITIONS INSERTED USING MUCOSA-SUPPORTED STEREOLITHOGRAPHIC SURGICAL GUIDE IN EDENTULOUS MANDIBLE AND MAXILLA

Omar M. Yehia , Marwa E. Sabet , Fardos N. Rizk And M. Shady Nabhan,

ABSTRACT


Purpose: Estimate The Deviation Between The Planned And The Actual Implant Inserted Using A Mucosa-supported Stereolithographic Surgical Guide In Different Edentulous Arches And Determine The Effect Of The Arch (mandible Or Maxilla) On Accuracy.

Materials and Methods: 16 Implants Were Placed In Completely Edentulous Arches And Divided Into Two Groups. Group (A): Eight Implants Were Placed In Four Patients In The Mandible Using Completely Limiting Mucosa-supported Stereolithographic (SLA) Surgical Guide During Implant Insertion. Two Implants Were Placed In Each Patient Intraforamina. Group (B): Eight Implants Were Placed In Two Patients In The Maxilla Using Completely Limiting Mucosa-supported Stereolithographic (SLA) Surgical Guide During Implant Insertion. Four Implants Were Placed In Each Patient In The Anterior Maxilla. Then The Deviation Between The Planned And The Actual Implant Positions Was Calculated.

Results: For The Maxilla, The Mean Angular Deviation 3.2mm With Standard Deviation �0.384, The Mean Coronal Deviation 1.88mm With Standard Deviation �0.37 And The Mean Apical Deviation 1.712 With Standard Deviation �0.24. For The Mandible, The Mean Angular Deviation 3.197mm With Standard Deviation �0.578, The Mean Coronal Deviation 1.56mm With Standard Deviation �0.38 And The Mean Apical Deviation 1.509 With Standard Deviation �0.173. Conclusion: Insignificant Difference In The Deviation Between The Planned And The Actual Implant Positions Between The Mandible And The Maxilla Placed By Stereolithographic Surgical Guide.

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EVALUATION OF THE EFFECT OF PROPOLIS VERSUS CALCIUM HYDROXIDE INTRACANAL MEDICAMENTS ON POST-OPERATIVE PAIN IN PATIENTS WITH NECROTIC PULP: A RANDOMIZED CLINICAL TRIAL (PART IV)

Fawzy Alshaimaa, El Far Hebatallah, Abou Elfotowh Elsayed And Elasfouri Heba,

ABSTRACT
This Study Was To Evaluate The Effect Of Propolis Compared To Calcium Hydroxide As Intracanal Medicaments On Postoperative Pain In Patients With Necrotic Pulp During Two Visit Treatment. Methods: Fifty Four Participants With Necrotic Pulp In Single Root Single Canal Teeth Were Included In This Study. After Confirming The Diagnosis Clinically And Radiographically, Access Cavity And Mechanical Preparation Using Were Accomplished In The Same Visit. Then Patients Were Randomly Assigned Into Two Equal Groups (calcium Hydroxide Group And Propolis Group), And Then The Access Cavity Was Sealed. Patients Were Instructed To Rate Their Pain Score At 24, 48, 72 Hours Then After 7 Days At The Day Of The Second Visit. After 7 Days The Intracanal Medicament Was Removed Then Root Canal Was Obturated.

Results: The Results Of This Study Showed That There Was No Statistically Significant Difference In Reduction Of Post-operative Pain Between Calcium Hydroxide Paste And Propolis Paste In Patient With Necrotic Pulp At 24 Hours, 72 Hours And 7 Days. However, There Was A Statistically Significant Difference In Reduction Of Post-operative Pain Between Two Groups At 48 Hours.

Conclusions: It Could Be Concluded That The Intracanal Use Of Calcium Hydroxide And Propolis Was Effective In Controlling Incidence And Intensity Of Post-operative Pain. The Intracanal Use Of Propolis Was Effective In Rapidly Controlling Post-operative Pain With No Side Effects.

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DETECTION OF CYTOMEGALOVIRUS IN MUCOEPIDERMOID CARCINOMA USING IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION TECHNIQUES

Nancy Abd Elrazik Abd Elhafiz, Heba Ahmed Farag And Dina Soliman Khater,

ABSTRACT
Background: Mucoepidermoid Carcinoma Is The Most Common Malignancy Of Salivary Glands And Therefore The Discovery Of Its Etiopathogenesis Would Be Of Critical Importance In Its Treatment And Management. Cytomegalovirus Is A Common Virus That Shows Tropism For Salivary Glands And Its Gene Products Can Promote Oncogenic Events That Directly Implicated In Malignant Progression. In This Study We Aimed To Detect The Presence Of Human Cytomegalovirus In Mucoepidermoid Carcinoma Which Could Give Idea About The Role Of This Virus In The Pathogenesis Of This Carcinoma.

Materials and Methods: 38 Archival Paraffin Embedded Specimens (8 Normal Salivary Gland Tissues, 30 MEC) Were Collected And Classified Into 20 Low Grade And 10 High Grade Mucoepidermoid Carcinoma. Specimens Were Evaluated By Immunohistochemistry And In Situ Hybridization For Evidence Of HCMV Antigens And Nucleic Acids.

Results: We Detected HCMV Proteins And Nucleic Acids In All MEC Specimens And Its Presence In 25% Of Normal Salivary Gland Tissue (control Group). Statistically Significant Difference Between High Grade, Low Grade And Control Group Was Observed (P<0.001). Conclusion: A Strong Association Between MEC And HCMV Was Observed Raising The Possibility Of The Viral Contribution In The Pathogenesis Of This Carcinoma.

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EVALUATION OF APICAL BACTERIAL LEAKAGE OF DIFFERENT ROOT END FILLING MATERIALS

Safaa M. Mohamed , Hayam Y. Hassan , Marwa M. Azab And Salma H. El Ashry,

ABSTRACT


Aim: Evaluate The Sealing Ability Of (Nano MTA, Biodentin And Fuji IX) Using Apical Bacterial Leakage Method With Two Different Techniques Of Root End Cavity Preparation Modern And Traditional Techniques After 1, 4 And 8 Weeks. Methods: Seventy Extracted Human Maxillary Anterior Teeth With Single Canal Were Distributed Into Two Equal Groups (30 Samples Each) According To Technique Of Root End Cavity Preparation Modern And Traditional Technique. 10 Teeth Were Used As Control (5 Roots Positive Group And 5 Roots Negative Group). The Main Groups Are Subdivided Into 3 Subgroups Corresponding To The Root End Filling Material Used, (Nano MTA, Biodentin And Fuji IX). Sealing Ability Was Assessed Using Enterococcus Faecalis (E. Faecalis) In A Double Chamber Leakage Model. Samples Were Monitored Weekly For Periods Of 1, 4 And 8 Weeks To Assess The Turbidity Of The Medium In Contact With The Lower Coronal Portion Of The Root Segment.

Results: Nano MTA And Biodentin Showed Low Bacterial Leakage With Modern Technique With No Statistically Significant Differences. But There Was Statistically Highly Significant Differences Found Between Fuji IX And Both Nano MTA And Biodentin (P � 0.05). Fuji IX Showed Maximum Leakage Value. Conclusion: Nano MTA And Biodentine Used With Modern Technique Showed A Significantly Better Sealing Ability. Microleakage Increased By Time With All Tested Materials

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FRACTURE RESISTANCE AND MODE OF FAILURE OF PREMOLAR RESTORED WITH LITHIUM DISILICATE VONLAY PARTIAL COVERAGE RESTORATIONS VERSUS LITHIUM DISILICATE ONLAY PARTIAL COVERAGE RESTORATIONS (IN-VITRO STUDY)

Nevien H. Hassab Alla And Omaima El-Mahallawi,

ABSTRACT


Aim: The Purpose Of This In-vitro Study Was To Compare The Fracture Resistance And Failure Modes Of Ceramic Partial Coverage Premolar Restorations Made Of A Lithium-disilicate Ceramic With Different Preparation Designs. Methods: Sixteen Human Maxillary Premolars Were Used In This Study. Teeth Were Chosen To Be Free From Any Caries, Defects, Or Cracks. To Facilitate Standardization Of Tooth Position During Preparation And During Test Procedure, Teeth Were Mounted In Epoxy Resin Blocks. Teeth Were Randomly Divided Into Four Groups (4 Each) According To Designs Of Preparation As Follows: Group A: (n= 4) Upper Premolars Restored With Lithium Disilicate Vonlay Partial Coverage. Group B: (n= 4) Upper Premolars Restored With Lithium Disilicate Partial Onlay Partial Coverage. Group C: (n= 4) Upper Premolars Restored With Lithium Disilicate Total Onlay Partial Coverage. Group D: (n= 4) Intact Teeth. Restorations Were Fabricated By IPS E.max Press Material, And Were Cemented On Epoxy Dies Using RelyX? Ultimate Resin Cement. All Samples Were Pre-loading In A Cyclic Manner Equivalent To The Average Masticatory Cycle. Afterward, Samples Were Loaded Until Fracture Using A Universal Test Machine. . Data Were Analyzed For Each Group Using One-way Analysis Of Variance (ANOVA); P Values Which Were 0.05 Or Less Were Considered Statistically Significant. The Fracture Mode Of All Samples Was Examined Using Stereomicroscope.

Results: The Highest Mean Value Of Maximum Load (Fracture Resistance) Was Found In Group A (vonlay) (1522.64 � 352.52) Followed By Group C (total Onlay) (1301.34 � 177.12) Followed By Group B (partial Onlay) (879.63 �158.92), The Least Mean Value Of Maximum Load (Fracture Resistance) Was Found In Group D (Intact Tooth) (717.33 � 198.59).

Conclusions: Within The Limitations Of This Study, All Fracture Resistance Loads Obtained In This Study Were Far Beyond The Maximum Masticatory Forces And

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EFFICACY OF THE THERAPEUTIC POTENTIAL OF GINGER (ZINGIBER OFFICINALE) ON THE SUBMANDIBULAR SALIVARY GLANDS IN STREPTOZOTOCIN ? INDUCED DIABETIC ALBINO RATS. (AN ANIMAL STUDY)

Sarah Mohamed Ellithy, Rabab Tawfik Mubarak And Dina B.E. Farag,

ABSTRACT
Background: Diabetes Mellitus Is The Most Common Metabolic Endocrine Disorder With Concomitant Oral Manifestation That Impact Dental Care. Ginger Is One Of The Most Commonly Consumed Dietary Condiments In The World. It?s Pharmacological And Physiological Actions Have Increased Over The Last Few Years. Objective: Investigate The Therapeutic Effect Of Aqueous Extract Of Zingiber Officinal On Submandibular Salivary Gland In Streptozotocin (STZ)-induced Diabetic Rats.

Materials and Methods: 24 Adult Male Albino Rats Were Utilized, Eight As Control Healthy Group (group I), Eight As STZ-induced Diabetic Group (group II) And Eight As Ginger (Zingiber Officinale) Treated Diabetic Group (group III). All The Animals In All Groups Were Sacrificed After 30 Days From The Beginning Of Ginger Extract Treatment. The Submandibular Salivary Glands Were Dissected And Examined Histologically, Immunohistochemically, And By Real-time Reverse Transcription Polymerase Chain Reaction (RT-PCR).

Results: Histologically, Diabetic Untreated Group (group II) Showed Marked Loss Of Acinar Architecture As Well As Degeneration In Duct System. Group III, Revealed Almost Normal Acinar And Ductal Histology. Immunohistochemically, There Was As Significant Statistical Decrease In The Expression Of NF-KB In Group III As Compared To Group II. RT-PCR Analysis Demonstrated A Statistical Significant Decrease In IL-2 MRNA Gene Expression In Group III As Compared To Group II.

Conclusions: Diabetes Led To Marked Histopathological Changes In Rat?s Submandibular Salivary Glands. Zingiber Officinale (ginger) Administration Led To Beneficial Pharmacological Effect Mainly Through Its Antioxidant And Anti-inflammtory Effect.

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