CLINICAL EVALUATION OF TOPICAL USE OF CO ENZYME Q10 IN MANAGEMENT OF RECURRENT ORAL APHTHOUS ULCERS: A RANDOMIZED CONTROLLED CLINICAL TRIAL

Mostafa A. Nafie, Amal A. Hussine And Fat?heya M Zahran,

ABSTRACT
Background: Recurrent Aphthous Stomatitis (RAS) Affects 20% Of The Population And Is Currently One Of The Most Common Oral Disorders. It Is An Inflammatory Condition Of Unknown Etiology Characterized By Recurrent, Painful, Single Or Multiple Ulcerations Of The Oral Mucosa. Various Treatment Modalities Such As Anti-inflammatory Agents, Steroids, Sucralfate, Tetracycline Suspension, Analgesics, Anesthetics, Antiseptics And, Recently, Anti-oxidants Are The Standard Topical Treatment Options That Provide Symptomatic Relief.

Aim: The Aim Of The Present Investigation Is To Evaluate The Clinical Effectiveness Of Coenzyme Q10 (CoQ10) Gel As An Anti-oxidant In The Management Of Idiopathic Recurrent Minor Oral Aphthous Ulcers In Patients Free From Any Systemic Condition. Subjects And Methods: The Present Study Was Conducted On 52 Patients (33 Males And 19 Females) Suffering From Symptomatic Oral Minor Aphthous Ulcers. Patients Were Randomly Divided Into Two Groups, One Of Them; The Intervention Group (A), Received Topical CoQ10 Gel In A 2% Concentration And The Other; Control Group (B), Received Carbopol Gel As Placebo. Each Group Contained 26 Patients (14 Males And12 Females In Group A And 19 Males And 7 Females In Group B) Who Were Instructed To Use Topical Oral Gel Delivered To Them In Sealed Opaque Jars, 2 Times /day After Breakfast And Evening Meals. Patients Were Evaluated At Initial Visit Day (day 0), Day 4 And Day 7, Using The Clinical Parameters Of Pain Score (VAS), Ulcer Size, Erythema Score And Healing Period.

Results: There Were Significant Differences In Reduction Of Pain, Size, Surrounding Erythema And Healing Period Of Ulcer Between The 2 Groups At Different Follow-up Intervals Within A Period Of 7 Days. Group A Showed Higher Significant Reduction In Pain, Ulcer Size And Erythema Compared With Group B Which Was Evident At 4th Day. Concerning The Healing Period, There Was Significant Difference Between Both Groups With P Value <0.001 In Favor Of Group A. Conclusion: Based On The Results Of The Current Study Co Enzyme Q10 Can Be Used As An Effective And Safe Agent In The Management Of RAS, Providing A Significantly Shorter Healing Period.

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THE INFLUENCE OF DIFFERENT CHEMICAL SURFACE TREATMENTS ON SHEAR BOND STRENGTH DURABILITY OF DUAL-CURED RESIN CEMENT TO CHAIR-SIDE RESIN COMPOSITE INDIRECT MATERIAL

Khaled Mohamed Adel, Zainab Diaa El-Din Soliman And Farid Sabry El-Askary .,

ABSTRACT
Objective: To Evaluate The Effect Of Different Chemical Surface Treatments On The Shear Bond Strength (SBS) Durability Of Resin Cement To A Chair Side Indirect Resin Composite Material.

Materials and Methods: In Total, 200 Resin Composite Discs (4mmx4mm) And 200 Resin Composite Cylinders (2mmx4mm) Were Prepared And Divided Into 20 Experimental Groups According To The Two Experimental Factors In This Study; Factor 1, Surface Treatment, 10 Groups [No-Treatment (NT); No-Treatment+Silane (NT+S); 35% Phosphoric Acid Etching (AE); 35% Phosphoric Acid Etching+Silane (AE+S); 9.5% Hydrofluoric Acid (HF); 9.5% Hydrofuoric Acid+Silane (HF+S); 30% Hydrogen Peroxide (HP); 30% Hydrogen Peroxide+Silane (HP+S); 20% Potassium Permanganate (PP) And 20% Potassium Permanganate+Silane (PP+S)] And Factor 2: Storage Time, 2 Groups [24 Hours And 1-year]. After Each Respective Surface Treatment, Each Resin Composite Cylinder Was Bonded To A Resin Composite Disc Using A Dual-cured Resin Cement. Half Of The Specimens Were Stored In Distilled Water For 24 Hours And The Other Half Was Stored In Distilled Water For 1-year. The SBS Testing Was Run At A Cross-head Speed Of 0.5mm/minute. Data Were Statistically Analyzed Using Two-way ANOVA/Tukey HSD Test. Significant Level Was Set At P=0.05. Additional 5 Resin Composite Discs (7mmx2mm) Were Examined Under SEM To Evaluate The Surface Topography After Each Chemical Treatment.

Results: Two-Way ANOVA Showed That Factors ?surface Treatment?, ?storage Time? And ?surface Treatment X Storage Time? Had Significant Effect On SBS (P<0.001). The NT And PP Groups Showed The Significant Lower SBS Among All Surface Treatments Used (P<0.05). The SBS Was Dropped Significantly After 1-year Storage Time In All Surface Treatment Used (P<0.05).

Conclusions: The SBS Of The Dual-cured Resin Cement To The Chair-side Resin Composite Indirect Material Was Not Stable After 1-year Storage Period.

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EFFECT OF PRE-HEATING TEMPERATURES ON MICROSHEAR BOND STRENGTH AND DEGREE OF CONVERSION OF A DUAL-CURED RESIN CORE FOUNDATION

Sara A. Botros, Zainab M. Soliman, Dalia I. El-Korashy And Farid S. El-Askary .,

ABSTRACT


Aim: To Evaluate The Effect Of Pre-heating Temperatures Of A Dual-cured Adhesive And A Dual-cured Resin Composite As Well As Tubule Orientation On Micro-shear Bond Strength (�SBS) To Dentin. The Degree Of Conversion (DC%) Of The Adhesive And The Composite Was Also Evaluated At The Different Temperatures.

Materials and Methods: For �SBS, 90 Human Molars Were Randomly Divided Into 18 Groups (n=5) According To The Three Experimental Factors. Factor 1: Adhesive Temperature, Factor 2: Resin Composite Temperature; And Factor 3: Tubule Orientation (occlusal Or Axial). Adhesive And Composite Temperatures Were Set At 25�C, 32�C And 40�C. The Adhesive Was Applied To Dentin According To Manufacturer Instructions. Each Occlusal Dentin Was Stored With Four Composite Micro-cylinders, While Each Axial Dentin Was Stored With Two Micro-cylinders. The �SBS Testing Was Run At A Crosshead Speed Of 1mm/min. The DC% Of Adhesive And Composite Was Evaluated At Each Temperature Using FTIR. Data Were Analyzed By ANOVA/Tukey?s HSD Post-hoc Test (P=0.05).

Results: Three-Way ANOVA Revealed That Only ?tubule Orientation? And ?adhesive Temperature X Composite Temperature? Had A Significant Effect On �SBS (P=0.001 And P=0.002, Respectively). For Occlusal Surfaces, ?adhesive Temperature?, ?composite Temperature? And ?adhesive Temperature X Composite Temperature? Had No Significant Effect On �SBS (P>0.05). For Axial Surfaces, ?adhesive Temperature?, ?composite Temperature? Showed No Significant Effect On �SBS (P>0.05), While ?adhesive Temperature X Composite Temperature? Had A Significant Effect On �SBS (P=0.002). The Predominant Failure Mode Was The Mixed Type (57.43%). The Three Temperatures Tested Showed No Significant Effect On The DC% Of The Adhesive. On The Contrary, Pre-heating The Resin Composite To 40�C Revealed A Significant Higher DC% Compared To 25�C. Conclusion: Tubular Orientation Seemed To Be An Influencing Factor On �SBS. Raising The Temperature To 40�C Improved The DC% Of Dual-cured Resin Composite, But Had No Effect On The Dual-cured Adhesive.

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EFFECT OF AGING ON SURFACE ROUGHNESS AND FRACTURE TOUGHNESS OF TWO DIFFERENT CADCAM MATERIALS

Ahmad M.M. Ali Goma?a And Manal Rafie Hassan,

ABSTRACT

Objectives: The Purpose Of This Study Is To Investigate The Aging By Thermocycling And Solutions With Different PH On Surface Roughness And Fracture Toughness Of Two Different CADCAM Materials.

Materials and Methods: Fifty Rectangular Samples (n=50) From Two Different CADCAM Materials. Vita Enamic CADCAM Blocks, Polymer Infiltrated Ceramics Blocks (En) And IPS E.max CADCAM Blocks, Lithium Disilicate Glass Ceramics Blocks (E Max). Samples Were Prepared Into Dimensions (14 X 2 X 1.5 Mm). . A Single Notch Was Prepared In Each Sample. The Notch Width Was Less Than Or Equal 0.3 Mm � 0.01mm. The Tip Of The Single Notch Was Located On The Long Surface Of The Sample At 0.24 To 0.48 Mm From The Bottom Left Corner. Samples Were Divided Into Two Main Groups, According To Type Of Material , Each Group Was Composed Of 25 Specimens, Each Group Further Divided Into Five Sub Group; Con= Control Group, Tc= Subjected To Thermocycling Only, Tc/N Stored In Neutral Media (Distilled Water PH7) + Thermocycling, Tc/Alk Stored In Alkaline Media (Sodium Bicarbonate PH 9) + Thermocycling, Tc/Ac Stored In Acidic Media (Coca Cola PH 2.2) + Thermocycling. Thermocycling Performed At 5-55oc For 10,000 Cycles. Aging In Solution Was Done At Room Temperature For 30 Days. Surface Roughness Measured For All Specimens By Profilometer Then Samples Subjected To 4 Points Bending Test Till Failure To Calculate Fracture Toughness. Data Presented As Mean And Standard Deviation (SD). Kolmogorov?Smirnov Test Used For Test Of Normality. Two-way ANOVA Used To Compare Between Groups And Subgroup Followed By Pairwise Comparison With Bonferroni Correction (�=0.05).

Results: Descriptive Statistics Showed Significant Difference Detected Between The Mean Values Of Both Type Of Ceramic. Vita Enamic Showed Higher Mean Surface Roughness (Ra) (?m). For Method Of Aging, Thermocycling (Tc) Group Showed The Grates Effect On Mean Surface Roughness (Ra) Followed By (Alk/Tc) Group. (N/Tc) Shows The Least Values Of Mean Surface Roughness (Ra). Descriptive Statistics Showed Significant Difference Detected Between The Mean Values Of Both Type Of Ceramic. IPS E.max CAD Shows Higher Mean Fracture Toughness (KIC) MPa (m1/2) Than Vita Enamic. For Method Of Aging, Thermocycling (Tc) Group Shows The Grates Effect On Mean Fracture Toughness (KIC) Followed By Other Three Groups With No Significant Difference Between The Three Of Them. Conclusion: Vita Enamic Showed Higher Surface Roughness Than IPS E.max CAD After Subjecting To Aging. IPS E.max CAD Showed Higher Fracture Toughness Than Vita Enamic After Subjecting To Aging.

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EVALUATION OF OSTEOSYNTHESIS MICROPLATES IN STABILIZATION OF IMMEDIATE IMPLANTS IN PERIODONTALLY INVOLVED TEETH

Bassem N. El Fahl, Mohammed M. Nassar, Hussein Saudi And Shereen A. Ali,

ABSTRACT


Purpose: To Evaluate Clinically And Radiographically The Success Of Dental Implants With Or Without Using Osteosynthesis Titanium Microplates In Replacement Of Periodontally Involved Teeth.

Materials and Methods: A Controlled Clinical Trial Designed On 18 Subjects With Periodontally Hopeless Teeth In Need To Dental Implants. All Subjects Received A Total Of 18 Implants, 9 In Each Group. One Group Received Dental Implant With Osteosynthesis Microplates Over Freeze Dried Bone Allograft (FDBA) And Collagen Membrane While The Other Group Received The Same Maneuver Without Osteosynthesis Microplates. Plaque Index [PI], Papillary Bleeding Index [PBI], Probing Pocket Depth [PPD], Clinical Attachment Level [CAL] And Dental Implant Stability [ISQ] Were Measured As Clinical Parameters. Facial Bone Thickness [FBT] And Facial Bone Density [FBD] Were Measured From CBCT Using Simplant Pro Software? (Dentsply Sirona Inc, Germany). Unpaired T-test Is Used To Compare Between Results Of Two Groups.

Results: Group-I Showed Statistically Significant Difference In Items Of ISQ, FBT And FBD Where PI, PPD, PBI And CAL Showed Non-statistically Significant Differences.

Conclusions: Osteosynthesis Microplates Can Be Used Successfully To Enhance And Assist Growing Facial Bone Thickness, Density And Stability Of Dental Implants With GBR.

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COMPARISON BETWEEN METAL-REINFORCED FLEXIBLE POLY-AMIDE COMPLETE DENTURE AND HEAT-CURED POLY-METHYL METHACRYLATE IN TERMS OF ORAL HEALTH RELATED QUALITY OF LIFE; (RANDOMIZED CLINICAL TRIAL)

Amr Magdy Ibrahim, Maha Wagdy El-Kerdawy And Ahmed Emad Fayyad,

ABSTRACT


Aim: This Study Was Conducted To Compare Between Conventional Heat-cured Poly-methyl Methacrylate (PMMA) Denture And Metal Re-enforced Polyamide Denture In Terms Of Oral Health Related Quality Of Life Using Oral Health Impact Profile For Edentulous Questionnaire, Readings Were Taken At One And Six Months.

Materials and Methods: Fourteen Patients Fulfilling The Eligibility Criteria Were Recruited From The Out-patient Clinic In The Prosthodontic Department, Faculty Of Dentistry, Cairo University. Conventional Steps For Complete Denture Construction Were Done And After Jaw Registration Phase The Patients Were Distributed Randomly Into Two Groups (seven Per Group) Where; The Control Group Received Heat-cured Polymethyl Methacrylate Maxillary And Mandibular Dentures, While The Intervention Group Received Heat Cured Polymethyl Methacrylate Maxillary Denture And Metal Reinforced Polyamide Mandibular Denture.

Results: All Patients Are Satisfied In The Control Group At One And Six Months With Mean Scores (17.71 And 17) Respectively And In The Intervention Group With Mean Scores (23 And 13.28) Respectively. Between The Two Groups There Was A Statistically Significant Difference At One Month Favoring Control Group, While There Was No Statistically Significant Difference At Six Months. Within The Control Group, There Was No Statistically Significant Difference Between One And Six Months. While Within The Intervention Group, There Was A Statistically Significant Difference Favoring Six Months. Conclusion: There Was No Effect Of Time On Oral Health Related Quality Of Life With The PMMA Dentures, While By Time There Was A Better Oral Health Related Quality Of Life With The Metal Re-enforced Polyamide Dentures Between One And Six Months.

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MARGINAL FIT OF HYBRID CERAMIC VERSUS LITHIUM DISILICATE MONOLITHIC RESTORATION WITH TWO FINISH LINE CURVATURE. INVITRO STUDY

Sally M. El Shennawy, Tamer A. Hamza And Ahmed Hassanien Khalil,

ABSTRACT
Statement Of Problem: Recently, Hybrid Ceramics Introduced Having Advantages Of Being Easily Processed And Time Saving. However, There Are Still Concerns About Marginal Accuracy With Different Finish Line Curvatures.

Purpose: The Purpose Of This In Vitro Study Was To Evaluate The Effect Of Two Finish Line Curvatures And Types Of Ceramic On Margin Fit Of Monolithic Restorations. Methodology: A Total Of 20 Monolithic Crowns Was Fabricated For This Thesis And Was Divided Into Two Groups According To Ceramics (Polymer Infiltrated Ceramics, Lithium Disilicate), And Each Group Will Be Further Subdivided Into Two Groups According To Finish Line Curvature (0mm And 3mm).The Crowns Was Placed On The Stainless Steel Dies And The Vertical Marginal Fit Was Evaluated With Sterio Digital Microscope At An Original Magnification Of X 30. The Results Were Tabulated And Statistically Analyzed With Using Kolmogorov-Smirnov And Shapiro-Wilk Tests. Kruskal-Wallis Test Was Used To Compare Between The Two Ceramic Types. Dunn?s Test Was Used For Pair-wise Comparisons When Kruskal-Wallis Test Is Significant. Mann-Whitney U Test Was Used To Compare Between The Two Finish Line Types.

Results: With Straight Finish Line; Lithium Disilicate Showed Statistically Significantly Higher Mean Marginal Gap Distance Than Polymer Infiltrated Ceramics. With Curved Finish Line; There Was No Statistically Significant Difference Between The Two Ceramic Types. In Addition, With Both Ceramic Types; There Was No Statistically Significant Difference Between The Two Finish Line Types.

Conclusions: Under The Circumstances Of This In Vitro Study, It Can Be Concluded That; The Polymer Infiltrated Ceramics Hybrid Restorations Had Superior Marginal Fit Than Lithium Disilicate And The Finish Line Curvatures Did Not Affect The Marginal Fit Of Tested Restorations. Clinical Implications: In The Light Of The Present Study; All Tested Samples Produced Marginal Fit Within Acceptable Range, So Can Be Used Clinically Providing Satisfactory Results.

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RETENTION OF COMPOSITE RESIN CORES CURED WITH TWO DIFFERENT MODES TO FIBER POST FOLLOWING SURFACE TREATMENT

Azza Mahmoud Sami El-sherif, Shereen Adel Amin And Carl Hany Halim,

ABSTRACT
The Aim Of This Study Was To Evaluate The Effect Of Fiber Post-head Surface Treatment On Its Retention To Two Composite Core Materials Cured With Two Curing Modes (light And Dual Polymerization).

Materials and Methods: A Total Number Of 30 Fiber Posts Were Used In This Study. Their Parallel Coronal Part Was The Part Mainly Used As We Test The Push Out Bond Strength Between Post Surface And Core Material. Posts Were Divided Into 3 Groups According To The Surface Treatment Each Containing 10 Posts: Group1: No Treatment (control), Group2: Air Abrasion (sandblasting) And Group3: Tribochemical Silica Coating (cojet). Silane Was Applied On All Posts Surface Following Surface Treatment As Indicated By The Post Manufacturer. The Groups Were Further Subdivided According To The Curing Mode Of The Composite Used To Build Up The Core Either Dual-cured Subgroup Or Light-cured Subgroup. Each Subgroup Contained 5 Posts.

Results: The Results Show That Curing Mode And Crown Region Have A Statistically Significant Effect On Mean Push-out Bond Strength. Surface Treatment Protocols As Well As The Interaction Between The Three Variables Have No Statistically Significant Effect On Mean Push-out Bond Strength. Since The Interaction Between The Variables Is Non-significant, So The Variables Are Independent From Each Other.

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DIAGNOSTIC UTILITY OF SHEARWAVE VELOCITY VALUES IN CHRONIC INFLAMMATORY CONDITIONS OF MAJOR SALIVARY GLANDS

Yasmein Maher El-beblawy And Maha Eshaq Amer Mohamed,

ABSTRACT
Objective The Aim Of This Study Was To Assess Chronic Inflammatory Conditions Of Major Salivary Glands By Shearwave Elastography. Patients And Methods 21 Patients With Chronic Inflammatory Conditions Of Major Salivary Glands And 21 Healthy Adult Volunteers Were Included In This Study. All Participants Underwent B-mode Sonography And Shearwave Elastography. The Diagnostic Performance Of Shearwave Velocity Was Evaluated By Sensitivity And Specificity At The Optimum Cutoff Point And The Area Under The Receiver Operating Characteristic Curve. Results Cases Showed Statistically Significantly Higher Median Shearwave Velocity Of Parotid Gland Than Control Group (P-value = 0.022, Effect Size = 1.119). There Was No Statistically Significant Difference Between Median SW Velocity Of Submandibular Gland In The Two Groups (P-value = 0.216, Effect Size = 0.576). As Regards The Total Scores; Cases Showed Statistically Significantly Higher Median Scores Than Control Group (P-value <0.001, Effect Size = 1.301). At Cut-off Value Of (23.5), Shearwave Velocity Showed 78.6% Diagnostic Accuracy With A Sensitivity Of 81% And Specificity Of 76.2% With 0.819 Area Under The Curve Of Receiver Operator Characteristics And Confidence Interval Was 0.669-0.920. Conclusion Shearwave Elastography Technique Might Be A Useful Noninvasive Strategy For Assessment Of Salivary Glands In Chronic Inflammatory Conditions.

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