EVALUATION OF THE EFFECT OF PROPOLIS VERSUS CALCIUM HYDROXIDE INTRACANAL MEDICAMENTS ON POST-OPERATIVE PAIN IN PATIENTS WITH NECROTIC PULP: A RANDOMIZED CLINICAL TRIAL (PART IV)

Fawzy Alshaimaa, El Far Hebatallah, Abou Elfotowh Elsayed And Elasfouri Heba,

ABSTRACT
This Study Was To Evaluate The Effect Of Propolis Compared To Calcium Hydroxide As Intracanal Medicaments On Postoperative Pain In Patients With Necrotic Pulp During Two Visit Treatment. Methods: Fifty Four Participants With Necrotic Pulp In Single Root Single Canal Teeth Were Included In This Study. After Confirming The Diagnosis Clinically And Radiographically, Access Cavity And Mechanical Preparation Using Were Accomplished In The Same Visit. Then Patients Were Randomly Assigned Into Two Equal Groups (calcium Hydroxide Group And Propolis Group), And Then The Access Cavity Was Sealed. Patients Were Instructed To Rate Their Pain Score At 24, 48, 72 Hours Then After 7 Days At The Day Of The Second Visit. After 7 Days The Intracanal Medicament Was Removed Then Root Canal Was Obturated.

Results: The Results Of This Study Showed That There Was No Statistically Significant Difference In Reduction Of Post-operative Pain Between Calcium Hydroxide Paste And Propolis Paste In Patient With Necrotic Pulp At 24 Hours, 72 Hours And 7 Days. However, There Was A Statistically Significant Difference In Reduction Of Post-operative Pain Between Two Groups At 48 Hours.

Conclusions: It Could Be Concluded That The Intracanal Use Of Calcium Hydroxide And Propolis Was Effective In Controlling Incidence And Intensity Of Post-operative Pain. The Intracanal Use Of Propolis Was Effective In Rapidly Controlling Post-operative Pain With No Side Effects.

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DETECTION OF CYTOMEGALOVIRUS IN MUCOEPIDERMOID CARCINOMA USING IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION TECHNIQUES

Nancy Abd Elrazik Abd Elhafiz, Heba Ahmed Farag And Dina Soliman Khater,

ABSTRACT
Background: Mucoepidermoid Carcinoma Is The Most Common Malignancy Of Salivary Glands And Therefore The Discovery Of Its Etiopathogenesis Would Be Of Critical Importance In Its Treatment And Management. Cytomegalovirus Is A Common Virus That Shows Tropism For Salivary Glands And Its Gene Products Can Promote Oncogenic Events That Directly Implicated In Malignant Progression. In This Study We Aimed To Detect The Presence Of Human Cytomegalovirus In Mucoepidermoid Carcinoma Which Could Give Idea About The Role Of This Virus In The Pathogenesis Of This Carcinoma.

Materials and Methods: 38 Archival Paraffin Embedded Specimens (8 Normal Salivary Gland Tissues, 30 MEC) Were Collected And Classified Into 20 Low Grade And 10 High Grade Mucoepidermoid Carcinoma. Specimens Were Evaluated By Immunohistochemistry And In Situ Hybridization For Evidence Of HCMV Antigens And Nucleic Acids.

Results: We Detected HCMV Proteins And Nucleic Acids In All MEC Specimens And Its Presence In 25% Of Normal Salivary Gland Tissue (control Group). Statistically Significant Difference Between High Grade, Low Grade And Control Group Was Observed (P<0.001). Conclusion: A Strong Association Between MEC And HCMV Was Observed Raising The Possibility Of The Viral Contribution In The Pathogenesis Of This Carcinoma.

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EVALUATION OF APICAL BACTERIAL LEAKAGE OF DIFFERENT ROOT END FILLING MATERIALS

Safaa M. Mohamed , Hayam Y. Hassan , Marwa M. Azab And Salma H. El Ashry ,

ABSTRACT


Aim: Evaluate The Sealing Ability Of (Nano MTA, Biodentin And Fuji IX) Using Apical Bacterial Leakage Method With Two Different Techniques Of Root End Cavity Preparation Modern And Traditional Techniques After 1, 4 And 8 Weeks. Methods: Seventy Extracted Human Maxillary Anterior Teeth With Single Canal Were Distributed Into Two Equal Groups (30 Samples Each) According To Technique Of Root End Cavity Preparation Modern And Traditional Technique. 10 Teeth Were Used As Control (5 Roots Positive Group And 5 Roots Negative Group). The Main Groups Are Subdivided Into 3 Subgroups Corresponding To The Root End Filling Material Used, (Nano MTA, Biodentin And Fuji IX). Sealing Ability Was Assessed Using Enterococcus Faecalis (E. Faecalis) In A Double Chamber Leakage Model. Samples Were Monitored Weekly For Periods Of 1, 4 And 8 Weeks To Assess The Turbidity Of The Medium In Contact With The Lower Coronal Portion Of The Root Segment.

Results: Nano MTA And Biodentin Showed Low Bacterial Leakage With Modern Technique With No Statistically Significant Differences. But There Was Statistically Highly Significant Differences Found Between Fuji IX And Both Nano MTA And Biodentin (P ? 0.05). Fuji IX Showed Maximum Leakage Value. Conclusion: Nano MTA And Biodentine Used With Modern Technique Showed A Significantly Better Sealing Ability. Microleakage Increased By Time With All Tested Materials

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FRACTURE RESISTANCE AND MODE OF FAILURE OF PREMOLAR RESTORED WITH LITHIUM DISILICATE VONLAY PARTIAL COVERAGE RESTORATIONS VERSUS LITHIUM DISILICATE ONLAY PARTIAL COVERAGE RESTORATIONS (IN-VITRO STUDY)

Nevien H. Hassab Alla And Omaima El-Mahallawi,

ABSTRACT


Aim: The Purpose Of This In-vitro Study Was To Compare The Fracture Resistance And Failure Modes Of Ceramic Partial Coverage Premolar Restorations Made Of A Lithium-disilicate Ceramic With Different Preparation Designs. Methods: Sixteen Human Maxillary Premolars Were Used In This Study. Teeth Were Chosen To Be Free From Any Caries, Defects, Or Cracks. To Facilitate Standardization Of Tooth Position During Preparation And During Test Procedure, Teeth Were Mounted In Epoxy Resin Blocks. Teeth Were Randomly Divided Into Four Groups (4 Each) According To Designs Of Preparation As Follows: Group A: (n= 4) Upper Premolars Restored With Lithium Disilicate Vonlay Partial Coverage. Group B: (n= 4) Upper Premolars Restored With Lithium Disilicate Partial Onlay Partial Coverage. Group C: (n= 4) Upper Premolars Restored With Lithium Disilicate Total Onlay Partial Coverage. Group D: (n= 4) Intact Teeth. Restorations Were Fabricated By IPS E.max Press Material, And Were Cemented On Epoxy Dies Using RelyX? Ultimate Resin Cement. All Samples Were Pre-loading In A Cyclic Manner Equivalent To The Average Masticatory Cycle. Afterward, Samples Were Loaded Until Fracture Using A Universal Test Machine. . Data Were Analyzed For Each Group Using One-way Analysis Of Variance (ANOVA); P Values Which Were 0.05 Or Less Were Considered Statistically Significant. The Fracture Mode Of All Samples Was Examined Using Stereomicroscope.

Results: The Highest Mean Value Of Maximum Load (Fracture Resistance) Was Found In Group A (vonlay) (1522.64 ? 352.52) Followed By Group C (total Onlay) (1301.34 ? 177.12) Followed By Group B (partial Onlay) (879.63 ?158.92), The Least Mean Value Of Maximum Load (Fracture Resistance) Was Found In Group D (Intact Tooth) (717.33 ? 198.59).

Conclusions: Within The Limitations Of This Study, All Fracture Resistance Loads Obtained In This Study Were Far Beyond The Maximum Masticatory Forces And

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EFFICACY OF THE THERAPEUTIC POTENTIAL OF GINGER (ZINGIBER OFFICINALE) ON THE SUBMANDIBULAR SALIVARY GLANDS IN STREPTOZOTOCIN ? INDUCED DIABETIC ALBINO RATS. (AN ANIMAL STUDY)

Sarah Mohamed Ellithy, Rabab Tawfik Mubarak And Dina B.E. Farag,

ABSTRACT
Background: Diabetes Mellitus Is The Most Common Metabolic Endocrine Disorder With Concomitant Oral Manifestation That Impact Dental Care. Ginger Is One Of The Most Commonly Consumed Dietary Condiments In The World. It?s Pharmacological And Physiological Actions Have Increased Over The Last Few Years. Objective: Investigate The Therapeutic Effect Of Aqueous Extract Of Zingiber Officinal On Submandibular Salivary Gland In Streptozotocin (STZ)-induced Diabetic Rats.

Materials and Methods: 24 Adult Male Albino Rats Were Utilized, Eight As Control Healthy Group (group I), Eight As STZ-induced Diabetic Group (group II) And Eight As Ginger (Zingiber Officinale) Treated Diabetic Group (group III). All The Animals In All Groups Were Sacrificed After 30 Days From The Beginning Of Ginger Extract Treatment. The Submandibular Salivary Glands Were Dissected And Examined Histologically, Immunohistochemically, And By Real-time Reverse Transcription Polymerase Chain Reaction (RT-PCR).

Results: Histologically, Diabetic Untreated Group (group II) Showed Marked Loss Of Acinar Architecture As Well As Degeneration In Duct System. Group III, Revealed Almost Normal Acinar And Ductal Histology. Immunohistochemically, There Was As Significant Statistical Decrease In The Expression Of NF-KB In Group III As Compared To Group II. RT-PCR Analysis Demonstrated A Statistical Significant Decrease In IL-2 MRNA Gene Expression In Group III As Compared To Group II.

Conclusions: Diabetes Led To Marked Histopathological Changes In Rat?s Submandibular Salivary Glands. Zingiber Officinale (ginger) Administration Led To Beneficial Pharmacological Effect Mainly Through Its Antioxidant And Anti-inflammtory Effect.

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CLINICAL EVALUATION OF TOPICAL USE OF CO ENZYME Q10 IN MANAGEMENT OF RECURRENT ORAL APHTHOUS ULCERS: A RANDOMIZED CONTROLLED CLINICAL TRIAL

Mostafa A. Nafie, Amal A. Hussine And Fat?heya M Zahran,

ABSTRACT
Background: Recurrent Aphthous Stomatitis (RAS) Affects 20% Of The Population And Is Currently One Of The Most Common Oral Disorders. It Is An Inflammatory Condition Of Unknown Etiology Characterized By Recurrent, Painful, Single Or Multiple Ulcerations Of The Oral Mucosa. Various Treatment Modalities Such As Anti-inflammatory Agents, Steroids, Sucralfate, Tetracycline Suspension, Analgesics, Anesthetics, Antiseptics And, Recently, Anti-oxidants Are The Standard Topical Treatment Options That Provide Symptomatic Relief.

Aim: The Aim Of The Present Investigation Is To Evaluate The Clinical Effectiveness Of Coenzyme Q10 (CoQ10) Gel As An Anti-oxidant In The Management Of Idiopathic Recurrent Minor Oral Aphthous Ulcers In Patients Free From Any Systemic Condition. Subjects And Methods: The Present Study Was Conducted On 52 Patients (33 Males And 19 Females) Suffering From Symptomatic Oral Minor Aphthous Ulcers. Patients Were Randomly Divided Into Two Groups, One Of Them; The Intervention Group (A), Received Topical CoQ10 Gel In A 2% Concentration And The Other; Control Group (B), Received Carbopol Gel As Placebo. Each Group Contained 26 Patients (14 Males And12 Females In Group A And 19 Males And 7 Females In Group B) Who Were Instructed To Use Topical Oral Gel Delivered To Them In Sealed Opaque Jars, 2 Times /day After Breakfast And Evening Meals. Patients Were Evaluated At Initial Visit Day (day 0), Day 4 And Day 7, Using The Clinical Parameters Of Pain Score (VAS), Ulcer Size, Erythema Score And Healing Period.

Results: There Were Significant Differences In Reduction Of Pain, Size, Surrounding Erythema And Healing Period Of Ulcer Between The 2 Groups At Different Follow-up Intervals Within A Period Of 7 Days. Group A Showed Higher Significant Reduction In Pain, Ulcer Size And Erythema Compared With Group B Which Was Evident At 4th Day. Concerning The Healing Period, There Was Significant Difference Between Both Groups With P Value <0.001 In Favor Of Group A. Conclusion: Based On The Results Of The Current Study Co Enzyme Q10 Can Be Used As An Effective And Safe Agent In The Management Of RAS, Providing A Significantly Shorter Healing Period.

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THE INFLUENCE OF DIFFERENT CHEMICAL SURFACE TREATMENTS ON SHEAR BOND STRENGTH DURABILITY OF DUAL-CURED RESIN CEMENT TO CHAIR-SIDE RESIN COMPOSITE INDIRECT MATERIAL

Khaled Mohamed Adel, Zainab Diaa El-Din Soliman And Farid Sabry El-Askary,

ABSTRACT
Objective: To Evaluate The Effect Of Different Chemical Surface Treatments On The Shear Bond Strength (SBS) Durability Of Resin Cement To A Chair Side Indirect Resin Composite Material.

Materials and Methods: In Total, 200 Resin Composite Discs (4mmx4mm) And 200 Resin Composite Cylinders (2mmx4mm) Were Prepared And Divided Into 20 Experimental Groups According To The Two Experimental Factors In This Study; Factor 1, Surface Treatment, 10 Groups [No-Treatment (NT); No-Treatment+Silane (NT+S); 35% Phosphoric Acid Etching (AE); 35% Phosphoric Acid Etching+Silane (AE+S); 9.5% Hydrofluoric Acid (HF); 9.5% Hydrofuoric Acid+Silane (HF+S); 30% Hydrogen Peroxide (HP); 30% Hydrogen Peroxide+Silane (HP+S); 20% Potassium Permanganate (PP) And 20% Potassium Permanganate+Silane (PP+S)] And Factor 2: Storage Time, 2 Groups [24 Hours And 1-year]. After Each Respective Surface Treatment, Each Resin Composite Cylinder Was Bonded To A Resin Composite Disc Using A Dual-cured Resin Cement. Half Of The Specimens Were Stored In Distilled Water For 24 Hours And The Other Half Was Stored In Distilled Water For 1-year. The SBS Testing Was Run At A Cross-head Speed Of 0.5mm/minute. Data Were Statistically Analyzed Using Two-way ANOVA/Tukey HSD Test. Significant Level Was Set At P=0.05. Additional 5 Resin Composite Discs (7mmx2mm) Were Examined Under SEM To Evaluate The Surface Topography After Each Chemical Treatment.

Results: Two-Way ANOVA Showed That Factors ?surface Treatment?, ?storage Time? And ?surface Treatment X Storage Time? Had Significant Effect On SBS (P<0.001). The NT And PP Groups Showed The Significant Lower SBS Among All Surface Treatments Used (P<0.05). The SBS Was Dropped Significantly After 1-year Storage Time In All Surface Treatment Used (P<0.05).

Conclusions: The SBS Of The Dual-cured Resin Cement To The Chair-side Resin Composite Indirect Material Was Not Stable After 1-year Storage Period.

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EFFECT OF PRE-HEATING TEMPERATURES ON MICROSHEAR BOND STRENGTH AND DEGREE OF CONVERSION OF A DUAL-CURED RESIN CORE FOUNDATION

Sara A. Botros, Zainab M. Soliman, Dalia I. El-Korashy And Farid S. El-Askary,

ABSTRACT


Aim: To Evaluate The Effect Of Pre-heating Temperatures Of A Dual-cured Adhesive And A Dual-cured Resin Composite As Well As Tubule Orientation On Micro-shear Bond Strength (?SBS) To Dentin. The Degree Of Conversion (DC%) Of The Adhesive And The Composite Was Also Evaluated At The Different Temperatures.

Materials and Methods: For ?SBS, 90 Human Molars Were Randomly Divided Into 18 Groups (n=5) According To The Three Experimental Factors. Factor 1: Adhesive Temperature, Factor 2: Resin Composite Temperature; And Factor 3: Tubule Orientation (occlusal Or Axial). Adhesive And Composite Temperatures Were Set At 25?C, 32?C And 40?C. The Adhesive Was Applied To Dentin According To Manufacturer Instructions. Each Occlusal Dentin Was Stored With Four Composite Micro-cylinders, While Each Axial Dentin Was Stored With Two Micro-cylinders. The ?SBS Testing Was Run At A Crosshead Speed Of 1mm/min. The DC% Of Adhesive And Composite Was Evaluated At Each Temperature Using FTIR. Data Were Analyzed By ANOVA/Tukey?s HSD Post-hoc Test (P=0.05).

Results: Three-Way ANOVA Revealed That Only ?tubule Orientation? And ?adhesive Temperature X Composite Temperature? Had A Significant Effect On ?SBS (P=0.001 And P=0.002, Respectively). For Occlusal Surfaces, ?adhesive Temperature?, ?composite Temperature? And ?adhesive Temperature X Composite Temperature? Had No Significant Effect On ?SBS (P>0.05). For Axial Surfaces, ?adhesive Temperature?, ?composite Temperature? Showed No Significant Effect On ?SBS (P>0.05), While ?adhesive Temperature X Composite Temperature? Had A Significant Effect On ?SBS (P=0.002). The Predominant Failure Mode Was The Mixed Type (57.43%). The Three Temperatures Tested Showed No Significant Effect On The DC% Of The Adhesive. On The Contrary, Pre-heating The Resin Composite To 40?C Revealed A Significant Higher DC% Compared To 25?C. Conclusion: Tubular Orientation Seemed To Be An Influencing Factor On ?SBS. Raising The Temperature To 40?C Improved The DC% Of Dual-cured Resin Composite, But Had No Effect On The Dual-cured Adhesive.

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EFFECT OF AGING ON SURFACE ROUGHNESS AND FRACTURE TOUGHNESS OF TWO DIFFERENT CAD\CAM MATERIALS

Ahmad M.M. Ali Goma?a And Manal Rafie Hassan,

ABSTRACT

Objectives: The Purpose Of This Study Is To Investigate The Aging By Thermocycling And Solutions With Different PH On Surface Roughness And Fracture Toughness Of Two Different CAD\CAM Materials.

Materials and Methods: Fifty Rectangular Samples (n=50) From Two Different CAD\CAM Materials. Vita Enamic CAD\CAM Blocks, Polymer Infiltrated Ceramics Blocks (En) And IPS E.max CAD\CAM Blocks, Lithium Disilicate Glass Ceramics Blocks (E Max). Samples Were Prepared Into Dimensions (14 X 2 X 1.5 Mm). . A Single Notch Was Prepared In Each Sample. The Notch Width Was Less Than Or Equal 0.3 Mm ? 0.01mm. The Tip Of The Single Notch Was Located On The Long Surface Of The Sample At 0.24 To 0.48 Mm From The Bottom Left Corner. Samples Were Divided Into Two Main Groups, According To Type Of Material , Each Group Was Composed Of 25 Specimens, Each Group Further Divided Into Five Sub Group; Con= Control Group, Tc= Subjected To Thermocycling Only, Tc/N Stored In Neutral Media (Distilled Water PH7) + Thermocycling, Tc/Alk Stored In Alkaline Media (Sodium Bicarbonate PH 9) + Thermocycling, Tc/Ac Stored In Acidic Media (Coca Cola PH 2.2) + Thermocycling. Thermocycling Performed At 5-55oc For 10,000 Cycles. Aging In Solution Was Done At Room Temperature For 30 Days. Surface Roughness Measured For All Specimens By Profilometer Then Samples Subjected To 4 Points Bending Test Till Failure To Calculate Fracture Toughness. Data Presented As Mean And Standard Deviation (SD). Kolmogorov?Smirnov Test Used For Test Of Normality. Two-way ANOVA Used To Compare Between Groups And Subgroup Followed By Pairwise Comparison With Bonferroni Correction (?=0.05).

Results: Descriptive Statistics Showed Significant Difference Detected Between The Mean Values Of Both Type Of Ceramic. Vita Enamic Showed Higher Mean Surface Roughness (Ra) (?m). For Method Of Aging, Thermocycling (Tc) Group Showed The Grates Effect On Mean Surface Roughness (Ra) Followed By (Alk/Tc) Group. (N/Tc) Shows The Least Values Of Mean Surface Roughness (Ra). Descriptive Statistics Showed Significant Difference Detected Between The Mean Values Of Both Type Of Ceramic. IPS E.max CAD Shows Higher Mean Fracture Toughness (KIC) MPa (m1/2) Than Vita Enamic. For Method Of Aging, Thermocycling (Tc) Group Shows The Grates Effect On Mean Fracture Toughness (KIC) Followed By Other Three Groups With No Significant Difference Between The Three Of Them. Conclusion: Vita Enamic Showed Higher Surface Roughness Than IPS E.max CAD After Subjecting To Aging. IPS E.max CAD Showed Higher Fracture Toughness Than Vita Enamic After Subjecting To Aging.

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EVALUATION OF OSTEOSYNTHESIS MICROPLATES IN STABILIZATION OF IMMEDIATE IMPLANTS IN PERIODONTALLY INVOLVED TEETH

Bassem N. El Fahl, Mohammed M. Nassar, Hussein Saudi And Shereen A. Ali,

ABSTRACT


Purpose: To Evaluate Clinically And Radiographically The Success Of Dental Implants With Or Without Using Osteosynthesis Titanium Microplates In Replacement Of Periodontally Involved Teeth.

Materials and Methods: A Controlled Clinical Trial Designed On 18 Subjects With Periodontally Hopeless Teeth In Need To Dental Implants. All Subjects Received A Total Of 18 Implants, 9 In Each Group. One Group Received Dental Implant With Osteosynthesis Microplates Over Freeze Dried Bone Allograft (FDBA) And Collagen Membrane While The Other Group Received The Same Maneuver Without Osteosynthesis Microplates. Plaque Index [PI], Papillary Bleeding Index [PBI], Probing Pocket Depth [PPD], Clinical Attachment Level [CAL] And Dental Implant Stability [ISQ] Were Measured As Clinical Parameters. Facial Bone Thickness [FBT] And Facial Bone Density [FBD] Were Measured From CBCT Using Simplant Pro Software? (Dentsply Sirona Inc, Germany). Unpaired T-test Is Used To Compare Between Results Of Two Groups.

Results: Group-I Showed Statistically Significant Difference In Items Of ISQ, FBT And FBD Where PI, PPD, PBI And CAL Showed Non-statistically Significant Differences.

Conclusions: Osteosynthesis Microplates Can Be Used Successfully To Enhance And Assist Growing Facial Bone Thickness, Density And Stability Of Dental Implants With GBR.

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