Seham Hazem El-Ayouti, Hend Mohammed Waguih , Nermine Raouf Amin And Enji Ahmed Mahmoud ,

ABSTRACT
Background: Oral Lichen Planus (OLP) Is A Chronic Immunologic Disorder. Patients With OLP Have An Increased Risk Of Developing Oral Squamous Cell Carcinoma (OSCC). Smoking Is Associated With Potentially Malignant Disorders Of The Oral Mucosa As OLP. In This Study We Aimed To Determine The Effect Of Smoking On ABCG2 Protein Expression In OLP Patients As An Assessment For Malignant Transformation.

Materials and Methods: Patients Were Divided Into Four Groups; 10 Individuals In Each Group With A Total Number Of 40 Individuals As Follows: Group I: Non-smoker Control, Group II: Smoker Control, Group III: Non-smoker Patients With OLP And Group IV: Smoker Patients With OLP. Area Percent Of Immunohistochemical Expression Of ABCG2 Was Measured By Software Leica Qwin 500.

Results: The Greatest Mean Area Percent Was Recorded In Lichen/ Smoker Group, Whereas The Lowest Value Was Recorded In The Control Group. The Difference Between All Groups Was Not Statistically Significant. Conclusion: ABCG2 Could Not Be Used As A Predictor For Malignant Transformation In Smoker OLP Patients As It Was Not Significantly Overexpressed In These Patients.

Amira Aboalnaga, Mona Salah Fayed And Sanaa Abo Zeid,

ABSTRACT
Background: Among The Recent Modalities Introduced To Accelerate Orthodontic Tooth Movement (OTM) Is Micro-osteoperforations (MOPs), Literally Meaning Puncturing Of Bone. Objective: The Primary Aim Of This Split-mouth Study Was To Evaluate The Effect Of (MOPs) On The Rate Of (OTM). Methods: 18 Patients Who Required Maxillary Canine Retraction Into First Premolar Extraction Sites As Part Of Their Orthodontic Treatment Completed This Study. Leveling And Alignment Proceeded Till 0.016? ? 0.022? NiTi Upper Archwire, Indirect Skeletal Anchorage Was Prepared, Then The Patients Were Referred For Upper 1st Premolars Extraction. Three Months Later, 0.017? ? 0.025? Stainless-steel Upper Archwire Was Inserted And Three Vertically Aligned MOPs Were Performed Distal To The Canine Using A Single TAD Unilaterally, While The Other Side Served As Control. NiTi Closing Coil Springs Delivering 150 Gms Of Force Were Used For Canine Retraction. Data Were Collected From Monthly Upper Impressions, Which Were Used To Obtain Digital Models, In Addition To Pre- And Post-retraction Maxillary CBCT Images.

Results: The Mean Difference Of The Distance Traveled By The Canine Cusp Tip Was Greater In The MOP Group Than The Control Group By (0.06 ? 0.7mm) (P > 0.05(. The Mean Differences Of The Distance Traveled By The Canine Center And Apex Were Significantly Greater In The MOP Group Than The Control Group By (0.37 ? 0.63 Mm, P < 0.05( And (0.47 ? 0.56 Mm, P < 0.01) Respectively.

Conclusions: Within The Limitations Of This Study, The Micro-osteoperforations Seemed To Facilitate Root Movement Yielding More Bodily Canine Retraction.

Heba-T-Allah Mohamed Mohamed Metwally, Inas Mohy El-Din, Shaymaa Mohamed Nagi. And Rasha Haridy,

ABSTRACT


Aim: This Study Was Conducted To Study The Effect Of Curing Mode Of Acetone-based Vs. Solvent-free Self-etch Adhesive Systems On The Resin-dentin Bond Strength At Different Dentin Depth And Time Intervals.

Materials and Methods: A Total Of 120 Recently Extracted Caries-free Human Molars Were Selected. Three Adhesive Systems Were Tested In This Study; [Nano-Bond? Two-step Acetone Based Self-etch Adhesive (NB)], [Nano-Bond? Two-step Acetone Based Self-etch Adhesive + Nano-Bond? Dual Cure Activator (NB+DC)], And [Bond-1 SF Solvent Free One-step SE Adhesive (SF)]. Teeth Were Prepared Either To Expose Superficial Or Deep Dentin. The Prepared Dentin Specimens Received The Adhesive Systems Of Each Subgroup According To The Manufacturer?s Instructions. Resin Composite Was Build Up On Bounded Dentin Substrate. Restored Specimens Were Aged Either For 48h Or Three Months, Then Each Restored Tooth Was Sectioned Into Sticks Of (1 ? 0.05) Mm2 Thickness To Be Tested For Microtensile Bond Strength (?TBS) Using Universal Lloyd Testing Machine Travelling At A Cross-head Speed Of 0.5 Mm/minute Until Failure.

Results: Results Revealed That (SF) Group Recorded The Highest Statistically Significant (p<0.05) ?TBS Mean Value (23.93? 1.04 MPa) Followed By (NB+DC) Group (22.97? 1.71 MPa), While (NB) Group Recorded The Lowest Statistically Significant (p<0.05) ?TBS Mean Value (21.22? 0.43 MPa) As Indicated By Three-way ANOVA Test. There Was Non-significant (p>0.05) Differences Between (SF) And (NB+DC). Moreover; There Was No Significant (p>0.05) Differences Between (NB+DC) And (NB). There Was No Statistical Significant Effect For Either Dentin Depth Or Aging Periods On Resin-dentin Microtensile Bond Strength Of All Tested Adhesive.

Conclusions: Solvent Free Light Cure Dentin Adhesive May Constitute A Promising Adhesive Concerning The ?TBS Irrespective Of Either Dentin Depth Or Time Intervals. Adding A Dual Cure Activator To Acetone Base Dentin Adhesive May Had No Obvious Benefits On The Resin-dentin ?TBS Regardless Dentin Depth And Time Intervals.

Ahmed Nasef Abdelhameed And Wael Mohamed Mubarak. Refai,

ABSTRACT
Abstract:

Aim: The Study Was Conducted To Provide A Three Dimensional Evaluation Of The Synergistic Effect Resulting From Combined Low Energy Laser Application And Micro-Osteoperforations On The Maxillary Canine Retraction In Orthodontic Patients. Patients And Methods: Three Parallel Groups (each Group Contained 10 Patients) Were Performed; Group A: Split Mouth Study Design In Which One Side Was Control Side And The Other Side Received Micro-osteoperforations (MOPs), Group B: Split Mouth Study Design In Which One Side Was Control Side And The Other Side Received Low Level Laser Therapy (LLLT), Group C: Split Mouth Study Design In Which One Side Was Control Side And The Other Side Received Both MOPs And LLLT. All Patients Were Radiographed By CBCT Images Before And After Canine Retraction And DDS-Pro Soft-ware Was Used For Evaluation Of The Maxillary Canine Retraction.

Results: Significant Statistical Differences Were Obvious In The Rate Of Canine Retraction Between Each Intervention And The Control Sides As Follow; The Mean Distance Travelled By The Canine Cusp Tip Point Relative To The Frontal Plane In Three Months In The Control Group Was 2.25 Mm?1.46 Mm, In The MOPs Group Was 3.86 Mm?1.56 Mm, In The LLLT Group Was 3.55 Mm?1.63 And In The Combined MOPs& LLLT Group Was 4.81 Mm?1.56 Mm. Conclusion: MOPs Technique Has The Ability To Accelerate The Rate Of Canine Retraction More Than The Application Of LLLT As Compared To The Standard Canine Retraction Technique. Moreover: Combination Of MOPs And LLLT Proved To Be More Efficient Regarding Increasing The Rate Of Canine Retraction Than The Application Of Each Technique Separately.

Gehan El Desouky , Abd El Badee Abdallah, Hany Shalaby And Hassan El Sayed Mohammed,

ABSTRACT


Aim: Assess The Outcome Of PRF Clots And Beta Tricalcium Phosphate As Sinus Graft Materiel With Simultaneous Implant Placement. Patient And Methods: Sixteen Patients Were Included In The Study Divided Into Two Groups As The First Control Group Sinus Augmentation Was Done Using Beta-TCP Alone And The Second Study Group Using Beta-TCP And PRF. Result: Using Beta-TCP Mixed With PRF Show Better Bone Density And Better Stability After 6 Months. Conclusion: The Use Of Beta-TCP Mixed With PRF As A Graft Materiel In Sinus Lifting Procedure Is Highly Superior To Beta-TCP Alone With Respect To The Implant Stability And Bone Density Around The Implant.

Salamah Almasry, Hamdi Abo Alfotooh And Mostafa Helmy,

ABSTRACT


Aim: Is To Compare The Stress Distribution Pattern In Two Different Attachment Systems Namely: Bar\clip. And Ball\socket. In Implant Supported Overdenture At Different Zones In Bone Surrounding Dental Implant With Application Of Force With Different Magnitudes And Directions Using 3D Finite Element Analysis. Material & Methods: 3d Model Of Two Edentulous Maxilla Restored With Implant Supported Overdenture Using Different Attachment Designs. Amount Of 50, 100 And 150 N Load In Deferent Directions (vertical And Oblique) Were Applied Through The Overdenture Simultaneously On Posterior Dentition By Aid Of Finite Element Analyses Software. Loads Were Directed Toward The Central Fossa. Stress Analysis Was Carried Out To Detect The Generated Stresses On Bone Surrounding Dental Implants.

Results: When Comparing Between Both Attachments, The Maximum Von Mises Stresses In Vertical Loads Of 50, 100, And 150 N And Both 50 N Oblique Loads. Ball Attachment Shows Lower Stress Levels At The Cancellous As Well As Cortical Bone Surrounding Dental Implants. Conclusion: The Maximum Von Mises Stresses In Both Models Among This Study Were Below The Critical Threshold Of Bone Resorption. The Region Which Displayed The Maximum Stress Concentration In The Both Models Was The Cortical Bone Surrounding The Loaded Implants. Bar\clip Attachment Recorded Higher Levels Of Von Mises Stresses Than Ball\socket In All Vertical And Oblique Loads.

Mostafa Mokhtar Anwar, Manal Mohamed Hosny; Engy Ahmed Mahmoud And Olfat Gamil Shaker,

ABSTRACT

Objectives: To Evaluate The Effect Of Systemic Administration Of Green Tea In Conjunction With Scaling And Root Planing Versus Scaling And Root Planning Alone On The GCF Total Oxidative Capacity And Clinical Parameters In Patients With Generalized Moderate Chronic Periodontitis. Methods: Twenty Eight Patients Participated In This Study And Were Randomly Allocated Into Two Groups: Group I (Test Group): Included 14 Patients (9 Females, 5 Males With Mean Age 40 Years) Received Scaling And Root Planing Then Patients Were Given Systemic Green Tea Tablets (300 Mg) To Be Taken Once Daily For 3 Months. Group II (Control Group): Included 14 Patients (7 Females, 7 Males With Mean Age 38 Years) Received The Same Treatment As In Group I Together With Systemic Placebo Tablets To Be Taken Once Daily For 3 Months. No Side Effects Were Reported After Green Tea Administration. The Clinical Parameters (PI, GI, PD And CAL) And TOC Were Recorded At Baseline And 3 Months After Treatment.

Results: Both Groups Showed Statistically Significant Improvement In All Clinical Parameters With No Difference Between Them. Test Group Showed More Statistically Significant Reduction In TOC Than The Control Group. Conclusion: Both The Test And Control Groups Exhibited Significant Improvement In Clinical Parameters And Significant Reduction In GCF Levels Of TOC 3 Months After Non- Surgical Periodontal Therapy. The Adjunctive Systemic Administration Of Green Tea Produced More Significant Reduction In GCF Levels Of TOC Compared To Control Group 3 Months After Non- Surgical Periodontal Therapy.

Amr Helmy Moustafa El Bolok, Safaa Marzouk Tohamy, Sherif Farouk Elgayar, Hanan Eid Gamal And Hiam Rifaat Hussien,

ABSTRACT
Background: Doxorubicin Is An Effective Cytotoxic Anticancer Agent And Has Been Used For The Treatment Of Variety Of Malignancies. The Aim Of The Current Study Is To Investigate The Effect Of Doxorubicin On Squamous Cell Carcinoma Cell Line (HEP-2) After 24 Hours. Material& Method: Treatment Of Cell Line (HEp-2) By Different Concentrations Of Doxorubicin Was Done To Assess The Viability Of The Treated Cells To Determine The Percentages Of Viable Cells That Was Monitored Using MTT Assay.

Results: The Mean Viability Percentage Of Doxorubicin Treated Cells (in Relation To Control Cells) Increased As Doxorubicin Concentration Decreased From 2000 MM To 1mM With An IC50 Of 9.5 MM. Regarding The Cytotoxic Effect Of Doxorubicin And Related Cell Cycle Profile It Was Noticed That Cell Distribution Showed A Variable Percent Of Arrest At Different Phase Of Cell Division Profile, Where There Was Non Significant Difference Of Arrested Cells Of Doxorubicin Pre And Post Treatment Compatred With Its Value In Non Treated G0-G1 Phase Control Cells(P>0.05) And S Phase As Well. While There Was A Significant Elevated Arrest Of Treated Cells During The G2-M Phase (P<0.05) And The Significant Difference Of Cell Arrest At G2-M Phase Was Type Of Treatment Related . Conclusion: From The Results Of The Current Study, We Found That Doxorubicin Has Cytotoxic Effect On Squamous Cell Carcinoma, (HEp-2) Cell Line, It Also Induced An Effect On The Cell Cycle Distribution, Persumtively Doxorubicin Has Effect On (HEp-2) Cell Line Resulting In Apoptosis And Necrosis.

Hady K. Abdelhalim, Kareem M. Gaber And Wael M.Refai,

ABSTRACT
Objective: To Propose Of New Software For Converting 2D Facial Photographs Into 3D Digital Models And Determine The Accuracy And Precision Of 3D Face Models Through An Indirect Facial Anthropometric Technique.

Materials and Methods: Ten Standard Linear And Horizontal Craniofacial Measurements Were Obtained From 22 Subjects Using The Proposed Software Inaddition To Five Angular Measurements And These Were Compared With Direct Anthropometry Through Digital Caliper.

Results: Mean Measurements Derived From Three-dimensional (3D) Images And Direct Anthropologic Measurements Were Mostly Similar However, Statistically Significant Differences Regarding Linear And Horizontal Measurements Were Noted For Four Measurements (Al-Al, Ch-Ch, N-Sn And Sn-Sto) . Regarding Angular Measurements Only Nasolabial Revealed Statistically Significant Difference.

Conclusions: Overall, Soft Tissue Facial Measurements (angles And Distances) On 3d Face Model Generated From Proposed Software Demonstrated Moderate Agreement, Accuracy And Precision With Traditional Anthropometry .

Abdullah AbdelBaky AlAfifi , Asmaa Yassen And Olfat Hassanein,

ABSTRACT

Objectives: Microhardness Evaluation Of Initial Enamel Lesions By Bioactive Glass Air-abrasion Before NovaMin Application. Methods: 40 Extracted Human Molars Were Sectioned Mesiodistally And Were Embedded In Resin Molds. Specimens Were Assigned To 4 Groups According To The Remineralization Protocol: G1- (artificial Saliva), G2- (air-abrasion), G3- (NovaMin), G4- (air-abrasion + NovaMin). Specimens Were Immersed In A Daily Renewed Demineralizing Solution To Create Artificial White Spot Lesions. Specimens Were Stored In A Daily Renewed Artificial Saliva. Microhardness Was Assessed Using Vicker?s Hardness Number (VHN) At Starting Point, After Demineralization, After 24 Hours And One Month Remineralization.

Results: The Group Of Air-abrasion That Received NovaMin For One Month Showed The Highest Statistically Significant VHN, With No Statistically Significant Difference Between The VHN Values Of This Group After Remineralization And At Starting Point.

Conclusions: Air-abrasion Of Enamel With Bioactive Glass Did Not Play A Role To Improve Remineralization.